{"id":"W1586425403","doi":"10.1111/tra.12292","title":"Multiple Domains in <scp>PEX16</scp> Mediate Its Trafficking and Recruitment of Peroxisomal Proteins to the <scp>ER</scp>","year":2015,"lang":"en","type":"article","venue":"Traffic","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; H2020 European Research Council; Johns Hopkins University","keywords":"Peroxisome; Endoplasmic reticulum; Biology; Cell biology; Function (biology); Cytosol; Protein targeting; Membrane protein; Biochemistry; Receptor; Enzyme; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001432002,0.0005142204,0.0002307438,0.0001517253,0.0002438222,0.0002911809,0.0003306006,0.0003890588,0.002140309],"category_scores_gemma":[0.0001414343,0.0001268409,0.0004077639,0.0001929253,0.0004291467,0.0003608339,0.000427882,0.0005538025,0.001359428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003501387,"about_ca_system_score_gemma":0.0003132474,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005763521,"about_ca_topic_score_gemma":0.0006164969,"domain_scores_codex":[0.9999275,0.00001314587,0.00001241818,0.00001688224,0.00001793643,0.00001216931],"domain_scores_gemma":[0.9998241,0.00003056045,0.00005791042,0.00002792082,0.00001592186,0.00004350638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001799398,0.00002057296,0.0006241917,0.00007279391,0.00001295418,0.0003287981,0.00002717442,0.0003138766,0.9960023,0.0004934531,0.00004551965,0.001878497],"study_design_scores_gemma":[0.00003440586,0.00011855,0.006438472,0.00001955502,0.0000163014,0.001295937,0.00004530836,0.001196674,0.9840844,0.0001727314,0.006568096,0.000009523224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990262,0.001522851,0.005714705,0.0001342342,0.00002804516,0.00003583246,0.0003873114,0.00008000142,0.001834905],"genre_scores_gemma":[0.9889313,0.0009175809,0.00507711,0.00008463989,0.000009063209,0.00005455025,0.001168723,0.00004281498,0.003714284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002140309,"threshold_uncertainty_score":0.007160068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03847501451542554,"score_gpt":0.2706961661150554,"score_spread":0.2322211515996299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}