{"id":"W1586905266","doi":"10.1002/0471142700.nc0312s23","title":"Nucleoside Phosphoramidites Containing Cleavable Linkers","year":2005,"lang":"en","type":"article","venue":"Current Protocols in Nucleic Acid Chemistry","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Phosphoramidite; Oligonucleotide; Oligonucleotide synthesis; Combinatorial chemistry; Linker; Nucleoside; Chemistry; Solid-phase synthesis; Duplex (building); DNA; Stereochemistry; Biochemistry; Peptide; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003844625,0.0008854897,0.0004158932,0.0002634869,0.0002042929,0.000356157,0.0006352763,0.0007245282,0.006524171],"category_scores_gemma":[0.0004800093,0.0005056814,0.0003217855,0.0003000752,0.0001888561,0.0004076265,0.0003908518,0.0009881882,0.005095763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003091528,"about_ca_system_score_gemma":0.0003030003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002010586,"about_ca_topic_score_gemma":0.0003322731,"domain_scores_codex":[0.9996808,0.00004811905,0.00003455281,0.00009350923,0.00008786314,0.00005521919],"domain_scores_gemma":[0.9997346,0.00007379344,0.00006239078,0.0000436287,0.00003670893,0.00004885782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009575469,0.00002749455,0.0000397924,0.0001617391,0.000007650079,0.00008010821,0.0000149582,0.0001185798,0.9920008,0.0005105654,0.0002811319,0.006661375],"study_design_scores_gemma":[0.00002487294,0.0001786245,0.0001209042,0.000008797136,0.00001597399,0.0002160635,0.000004101154,0.0002699436,0.9816664,0.00009723561,0.01738991,0.000007104537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.6046551,0.01671262,0.3243804,0.0005674693,0.000869592,0.001532924,0.003825378,0.006874481,0.04058201],"genre_scores_gemma":[0.6712334,0.01345431,0.2534284,0.000646473,0.0001381912,0.001856934,0.009374246,0.0009413462,0.04892668],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.006524171,"threshold_uncertainty_score":0.02182555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01759417180101145,"score_gpt":0.3227991480654567,"score_spread":0.3052049762644453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}