{"id":"W1586916519","doi":"10.1093/jnci/djt028","title":"RanGTPase: A Candidate for Myc-Mediated Cancer Progression","year":2013,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Queen's University Belfast; Cancer and Polio Research Fund","keywords":"Gene knockdown; Cancer; Breast cancer; Cancer research; Oncogene; Ran; Biology; Metastasis; Chromatin immunoprecipitation; Lung cancer; Oncology; Medicine; Internal medicine; Gene expression; Promoter; Cell culture; Gene; Cell cycle; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003423989,0.0006167005,0.0003853629,0.000449568,0.0003093696,0.0006869966,0.000530751,0.0005939493,0.003076564],"category_scores_gemma":[0.0005298354,0.000113761,0.0003533257,0.0003081794,0.0002937453,0.0004592903,0.0002987339,0.0005664121,0.0008149504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004087877,"about_ca_system_score_gemma":0.0002365886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001481501,"about_ca_topic_score_gemma":0.0001155341,"domain_scores_codex":[0.999854,0.00002744052,0.0000100897,0.00005716092,0.00002408172,0.00002723181],"domain_scores_gemma":[0.9995653,0.00009004476,0.0001799413,0.00002426859,0.00005869973,0.00008169509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003967661,0.0002414068,0.06129078,0.002049034,0.0003882528,0.009815423,0.0001957631,0.003477068,0.8053349,0.00992211,0.003620781,0.09969682],"study_design_scores_gemma":[0.0004552978,0.00462106,0.2102386,0.0006797847,0.0007323734,0.06818411,0.0005812101,0.02416679,0.5633333,0.01206151,0.1147891,0.0001568393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8498638,0.1031006,0.03449324,0.001680966,0.0004170922,0.0001911052,0.002467559,0.0006806804,0.007105009],"genre_scores_gemma":[0.9806046,0.008996919,0.005182794,0.0001101701,0.0001381772,0.00007109409,0.001857747,0.00001945646,0.00301906],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003076564,"threshold_uncertainty_score":0.01029211,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02118090872849381,"score_gpt":0.3291511755604423,"score_spread":0.3079702668319485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}