{"id":"W1587087382","doi":"","title":"Abstract #5543: Lovastatin induces apoptosis of ovarian cancer cells and modulates the efficacy of chemotherapeutics: Implications for patient treatment","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Lipids, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Lovastatin; Doxorubicin; Apoptosis; Statin; Ovarian cancer; Cancer research; HMG-CoA reductase; Pharmacology; Cancer; Cancer cell; Medicine; Chemotherapy; Biology; Cholesterol; Reductase; Internal medicine; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002168172,0.0004390719,0.0003863867,0.000396572,0.0003169538,0.000582782,0.0002565369,0.0005319901,0.02097436],"category_scores_gemma":[0.0001275228,0.000169489,0.0001633379,0.0004251328,0.0002400075,0.0001634541,0.0001999014,0.0007314086,0.007627516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007338095,"about_ca_system_score_gemma":0.0005066704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001922287,"about_ca_topic_score_gemma":0.004839828,"domain_scores_codex":[0.9998896,0.0000277717,0.000009734085,0.00001438846,0.00003415879,0.00002422096],"domain_scores_gemma":[0.9999368,0.00001379803,0.000007914515,0.000005481288,0.00001522378,0.00002080952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006087552,0.00133322,0.005247395,0.001012461,0.00007157142,0.001061827,0.0001310678,0.0004078267,0.6015331,0.001964185,0.08321127,0.2979385],"study_design_scores_gemma":[0.001302168,0.005237696,0.10656,0.0002192053,0.0001724468,0.004759129,0.0002126042,0.001933044,0.2849688,0.001097322,0.5934932,0.00004434054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5785257,0.1493483,0.004195616,0.03205621,0.003109751,0.000830332,0.005042695,0.001049149,0.2258424],"genre_scores_gemma":[0.736815,0.07016162,0.003900411,0.003877137,0.001595306,0.0003142,0.004309624,0.0001752244,0.1788516],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02097436,"threshold_uncertainty_score":0.07016623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05403544030168635,"score_gpt":0.3811715145736618,"score_spread":0.3271360742719755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}