{"id":"W1587740529","doi":"10.4254/wjh.v2.i3.103","title":"Medical treatment of unresectable hepatocellular carcinoma: Going beyond sorafenib","year":2010,"lang":"en","type":"article","venue":"World Journal of Hepatology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Hospital Foundation","funders":"","keywords":"Sorafenib; Medicine; Hepatocellular carcinoma; Vascular endothelial growth factor; Cancer research; Wnt signaling pathway; Growth factor; Growth factor receptor; Oncology; Internal medicine; Cancer; Bioinformatics; Signal transduction; VEGF receptors; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003463937,0.0001564401,0.0007915029,0.0003539413,0.0000464582,0.000005406569,0.000138596,0.000140664,0.002452698],"category_scores_gemma":[0.00005795235,0.0001136535,0.0002680596,0.0002195016,0.0001316441,0.0000495035,0.00002047101,0.0003989259,0.000009491658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008408615,"about_ca_system_score_gemma":0.0007067062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000180156,"about_ca_topic_score_gemma":0.0009535679,"domain_scores_codex":[0.9984701,0.00005620329,0.000637154,0.0001451003,0.0004085067,0.0002829166],"domain_scores_gemma":[0.9987611,0.0001229633,0.0003655213,0.0002480972,0.0001997469,0.0003025993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001937723,0.001208565,0.8085809,0.00008303055,0.0004595973,0.00478415,0.0005219294,0.000001302637,0.1407498,0.01178111,0.002056993,0.027835],"study_design_scores_gemma":[0.02874247,0.009859633,0.0136991,0.0002419601,0.0008565198,0.02162054,0.0001971872,0.00356563,0.4519448,0.007680929,0.4610752,0.0005160861],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99006,0.003500916,0.0002462055,0.002990143,0.001374985,0.0001387399,0.000003236841,0.000008600702,0.001677142],"genre_scores_gemma":[0.9965243,0.0004071688,0.001339629,0.0003075326,0.0005661483,0.000003933142,0.000002640182,0.00002287076,0.0008257489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7948818,"threshold_uncertainty_score":0.9984592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425747089633367,"score_gpt":0.2801913571193497,"score_spread":0.265933886223016,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}