{"id":"W1588990817","doi":"10.1186/1471-2164-6-18","title":"Identification of functional SNPs in the 5-prime flanking sequences of human genes","year":2005,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Research Foundation; Pfizer","keywords":"Single-nucleotide polymorphism; Biology; Genetics; Gene; 5' flanking region; Human genome; Conserved sequence; Computational biology; Promoter; Genome; Gene expression; Genotype; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007036532,0.0004579339,0.000421268,0.0008051064,0.0002083151,0.000214428,0.0002832011,0.0005283359,0.001314553],"category_scores_gemma":[0.001139478,0.0001620455,0.0004305821,0.0004898141,0.0002320729,0.0001133401,0.0002312219,0.0004700517,0.0005168139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001605688,"about_ca_system_score_gemma":0.0002880644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003142935,"about_ca_topic_score_gemma":0.0009797818,"domain_scores_codex":[0.99953,0.0001376262,0.0000396812,0.0001330586,0.0001167626,0.00004292206],"domain_scores_gemma":[0.9992033,0.0004387994,0.0001854473,0.00006862066,0.00004551317,0.00005839037],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006022188,0.0001203338,0.0366011,0.0002716145,0.0001060943,0.0007016353,0.000116919,0.001019177,0.9420028,0.0006077448,0.0002731239,0.01757723],"study_design_scores_gemma":[0.0001860062,0.001883527,0.348911,0.0001365588,0.0005476518,0.006508452,0.0001358464,0.009516366,0.6212415,0.001268201,0.009608815,0.00005613968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660617,0.001101528,0.02992491,0.0001356151,0.00003852939,0.0001314484,0.001740828,0.0001455065,0.0007199835],"genre_scores_gemma":[0.9424115,0.0003882817,0.05332735,0.0001753579,0.00003127139,0.0001176403,0.003050206,0.00003798288,0.0004605297],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001314553,"threshold_uncertainty_score":0.004397631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03291250038884439,"score_gpt":0.2814658017401091,"score_spread":0.2485533013512647,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}