{"id":"W1589170899","doi":"10.1111/j.1742-4658.2005.04927.x","title":"Serpins 2005 – fun between the β‐sheets","year":2005,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cambridge Institute for Medical Research, University of Cambridge; Centre for Blood Research, University of British Columbia; National Eye Institute; Medical School, University of Michigan; National Institutes of Health; University of Illinois at Chicago; University of Michigan","keywords":"Serpin; Protease; Biology; Proteolysis; Proteases; Eukaryote; Serine Proteinase Inhibitors; Serine protease; Biochemistry; Cell biology; Genome; Enzyme","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002354459,0.0008900283,0.0004333755,0.0005396269,0.0004763458,0.001036761,0.0004068606,0.000556069,0.006692008],"category_scores_gemma":[0.0003012369,0.000193082,0.0003049998,0.0003551375,0.0003262814,0.0008039147,0.000558374,0.0009183935,0.005078668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003645619,"about_ca_system_score_gemma":0.0003070069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001538146,"about_ca_topic_score_gemma":0.0001712114,"domain_scores_codex":[0.9998435,0.00002154224,0.0000126554,0.00003946965,0.00005981975,0.00002301708],"domain_scores_gemma":[0.9998809,0.00001142681,0.00003335125,0.000006866579,0.00002221714,0.0000452932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001053362,0.00007638377,0.001445847,0.00130484,0.0001260897,0.003518906,0.0001612984,0.0008001726,0.6252673,0.01493382,0.01987381,0.3314381],"study_design_scores_gemma":[0.00006196817,0.0004574192,0.004350481,0.0001714521,0.00007312616,0.009652659,0.0001370431,0.001153515,0.2500765,0.004458214,0.7293674,0.0000402675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3261586,0.4586262,0.03312943,0.004266597,0.008176074,0.0003254425,0.002058224,0.002044607,0.1652147],"genre_scores_gemma":[0.6340986,0.1440004,0.01953873,0.002390212,0.001347486,0.000129572,0.00391961,0.000170492,0.1944049],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006692008,"threshold_uncertainty_score":0.02238703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01115332414265119,"score_gpt":0.2453047921179927,"score_spread":0.2341514679753415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}