{"id":"W1589688567","doi":"10.4049/jimmunol.174.4.2353","title":"Decay-Accelerating Factor (CD55) Is Expressed by Neurons in Response to Chronic but Not Acute Autoimmune Central Nervous System Inflammation Associated with Complement Activation","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Decay-accelerating factor; Complement system; Classical complement pathway; Experimental autoimmune encephalomyelitis; Biology; Complement membrane attack complex; Cell biology; Complement receptor; Antibody opsonization; Immunology; Ectopic expression; Neuroprotection; CD59; Proinflammatory cytokine; Inflammation; Complement C1q; Microglia; C5a receptor; Innate immune system; Neuroscience; Immune system; Phagocytosis; Opsonin; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009505281,0.0002714063,0.0005322175,0.0002740177,0.0002857471,0.00003816227,0.0006388398,0.0001436103,0.0002833382],"category_scores_gemma":[0.0001705779,0.0001975841,0.0001069451,0.0002378019,0.0001100052,0.0002660527,0.00015396,0.0004884389,0.00004683028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001189589,"about_ca_system_score_gemma":0.0002668015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000123406,"about_ca_topic_score_gemma":0.0001281349,"domain_scores_codex":[0.9958987,0.002037071,0.001125795,0.0001932732,0.0001461311,0.0005990785],"domain_scores_gemma":[0.9974884,0.0007679703,0.001113745,0.0003786799,0.0002169909,0.00003422714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005481266,0.0001133899,0.0006270304,0.00001214015,0.0007888142,0.00000765115,0.001746704,0.000779713,0.9864292,0.0000298417,0.001264972,0.002719251],"study_design_scores_gemma":[0.005714347,0.001759172,0.3011752,0.0005363246,0.0001803925,0.0001696515,0.00171662,0.0001388381,0.6829018,0.000001991168,0.005411531,0.0002941543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932904,0.0008167529,0.000650165,0.004062471,0.0003238562,0.0006561041,0.0001277709,0.0000494301,0.00002308269],"genre_scores_gemma":[0.9994261,0.00003412168,0.00004183731,0.0001694038,0.00005590883,0.00002778824,0.00005514726,0.00002848925,0.0001612363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3035274,"threshold_uncertainty_score":0.8057248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0193959545151656,"score_gpt":0.2526519641454268,"score_spread":0.2332560096302612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}