{"id":"W1589688567","doi":"10.4049/jimmunol.174.4.2353","title":"Decay-Accelerating Factor (CD55) Is Expressed by Neurons in Response to Chronic but Not Acute Autoimmune Central Nervous System Inflammation Associated with Complement Activation","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council","keywords":"Decay-accelerating factor; Complement system; Classical complement pathway; Experimental autoimmune encephalomyelitis; Biology; Complement membrane attack complex; Cell biology; Complement receptor; Antibody opsonization; Immunology; Ectopic expression; Neuroprotection; CD59; Proinflammatory cytokine; Inflammation; Complement C1q; Microglia; C5a receptor; Innate immune system; Neuroscience; Immune system; Phagocytosis; Opsonin; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001888235,0.0002966964,0.0002500077,0.000245828,0.0001625178,0.0004016954,0.0001517306,0.0003374075,0.00062858],"category_scores_gemma":[0.0001593208,0.0001385929,0.0002555594,0.0001783541,0.000264124,0.0002265376,0.0002449707,0.0005311625,0.0002468932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004590928,"about_ca_system_score_gemma":0.0002056604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001046954,"about_ca_topic_score_gemma":0.0009242997,"domain_scores_codex":[0.9997897,0.00001866947,0.00002673931,0.00003999339,0.00004452387,0.00008040333],"domain_scores_gemma":[0.9998653,0.00001944719,0.00003827138,0.00001880254,0.00002403689,0.00003413862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001047583,0.000007280928,0.0002985501,0.00002163203,0.000004184164,0.0000548037,0.00002123905,0.000006711626,0.9991397,0.00002727146,0.000006665355,0.0003071327],"study_design_scores_gemma":[0.00003491589,0.0007761122,0.03972239,0.00002746956,0.00006065161,0.001197681,0.0002001168,0.000390665,0.9560093,0.0001246073,0.001446205,0.000009923536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976394,0.001176669,0.0005832401,0.00002786704,0.000009126507,0.00001047349,0.0001082902,0.00001119813,0.0004335961],"genre_scores_gemma":[0.996894,0.0009441251,0.0008318159,0.00003529598,0.000008990476,0.00002450095,0.0002289097,0.000005129115,0.001027168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001046954,"threshold_uncertainty_score":0.003330946,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0193959545151656,"score_gpt":0.2526519641454268,"score_spread":0.2332560096302612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}