{"id":"W1590526528","doi":"10.1111/j.1365-2249.2011.04376.x","title":"Efficacy and safety of home-based subcutaneous immunoglobulin replacement therapy in paediatric patients with primary immunodeficiencies","year":2011,"lang":"en","type":"article","venue":"Clinical & Experimental Immunology","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"CSL Behring","keywords":"Medicine; Adverse effect; Antibody; Immunoglobulin G; Pediatrics; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001162483,0.0001779678,0.0007450756,0.0001750478,0.00009134501,0.0002768473,0.0001735208,0.0002238656,0.0003355174],"category_scores_gemma":[0.002761353,0.00009357629,0.0003043195,0.000263602,0.0002442887,0.0001456958,0.0001320925,0.0003362074,0.00005701753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002411801,"about_ca_system_score_gemma":0.0003077272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005228865,"about_ca_topic_score_gemma":0.0005451854,"domain_scores_codex":[0.9993069,0.0004388622,0.00004866773,0.00004454292,0.0001257328,0.00003526889],"domain_scores_gemma":[0.9981076,0.0009194369,0.0006628344,0.00008062641,0.000106734,0.0001228107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02141587,0.001482215,0.7428138,0.00108158,0.0004952032,0.001774173,0.001019036,0.001535071,0.02223366,0.0001281319,0.0004972718,0.205524],"study_design_scores_gemma":[0.002111277,0.05570486,0.9269052,0.0001543938,0.0004320946,0.005261132,0.0002588973,0.001135084,0.005838501,0.00005722391,0.002122365,0.00001889739],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960674,0.003403655,0.0001286403,0.00002563072,0.000003061442,0.00001558368,0.00003424118,0.000007032903,0.0003146587],"genre_scores_gemma":[0.9985998,0.001000688,0.000250718,0.00002363349,0.00001141829,0.00001167976,0.00006763181,0.000001297452,0.00003310135],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162483,"threshold_uncertainty_score":0.006147861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01934156040555878,"score_gpt":0.2589793279175567,"score_spread":0.2396377675119979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}