{"id":"W1590614500","doi":"10.2353/ajpath.2007.061232","title":"Calpain-Cleavage of α-Synuclein","year":2007,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":237,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Center for Research Resources; National Institutes of Health","keywords":"Calpain; Cleavage (geology); Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004843607,0.00009580085,0.00048359,0.0002042936,0.00001922836,0.00000162845,0.00007630184,0.00003477047,0.00005960797],"category_scores_gemma":[0.00008962381,0.00007322767,0.0001657985,0.00017877,0.0002286823,0.00002900297,0.00001762424,0.0001412006,0.00001415513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000451311,"about_ca_system_score_gemma":0.00008173226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001340538,"about_ca_topic_score_gemma":0.00000214488,"domain_scores_codex":[0.9990305,0.00006462523,0.0004032982,0.000101099,0.0001893099,0.0002111252],"domain_scores_gemma":[0.9989254,0.00007471297,0.0005074695,0.0001520438,0.0001242052,0.0002161326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.003278025,0.002006148,0.1842363,0.00004992053,0.0006840628,0.04973168,0.001212583,0.000002927874,0.2108185,0.001550574,0.001210751,0.5452185],"study_design_scores_gemma":[0.00505643,0.01354568,0.8553845,0.0001369878,0.0007125388,0.01370268,0.002271666,0.000009308377,0.09662285,0.0008255417,0.01151951,0.0002123651],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934098,0.0002757766,0.003651118,0.0002089867,0.0001192783,0.00005444173,0.000005657334,0.000006431702,0.002268583],"genre_scores_gemma":[0.9909981,0.00005824521,0.008283212,0.0004886823,0.00009734947,4.401945e-7,0.000001233858,0.00001434445,0.00005834227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6711481,"threshold_uncertainty_score":0.2986138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01112234349920862,"score_gpt":0.2871190624036525,"score_spread":0.2759967189044439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}