{"id":"W1591039646","doi":"10.1016/j.ctrv.2015.05.006","title":"New molecular targets in non clear renal cell carcinoma: An overview of ongoing clinical trials","year":2015,"lang":"en","type":"review","venue":"Cancer Treatment Reviews","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Associazione Italiana per la Ricerca sul Cancro","keywords":"Medicine; PI3K/AKT/mTOR pathway; Renal cell carcinoma; Cancer research; Discovery and development of mTOR inhibitors; Targeted therapy; Immunotherapy; Clinical trial; Immunohistochemistry; Pathology; Oncology; Internal medicine; Bioinformatics; Cancer; Signal transduction; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001213607,0.0009837319,0.003198948,0.002126246,0.0002379554,0.001358643,0.001078554,0.001061467,0.004136316],"category_scores_gemma":[0.001378037,0.0003729698,0.001752068,0.002165973,0.0003562333,0.001322861,0.0006195354,0.001912499,0.0008419982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006294505,"about_ca_system_score_gemma":0.001406674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001145733,"about_ca_topic_score_gemma":0.003720897,"domain_scores_codex":[0.9997135,0.00006030713,0.0000577061,0.00004899836,0.00008750828,0.00003202102],"domain_scores_gemma":[0.9992561,0.00043133,0.0001308685,0.00001322673,0.0001277706,0.000040576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0005428037,0.0001824933,0.0003357689,0.07114685,0.0006883737,0.0001489111,0.00005981267,0.000715232,0.001857533,0.001630245,0.02006219,0.9026297],"study_design_scores_gemma":[0.0005634805,0.001328256,0.002985606,0.03865463,0.005034017,0.001342086,0.0001907355,0.0005783116,0.001415876,0.002794807,0.9450254,0.00008671476],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001221655,0.9993481,0.0000640489,0.0001197714,0.00006111479,0.00001004913,0.00002982058,0.000004361173,0.0002406396],"genre_scores_gemma":[0.0007791922,0.9985473,0.000191157,0.0002246551,0.00005707173,0.00001105938,0.00004144208,0.000001356527,0.0001466853],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004136316,"threshold_uncertainty_score":0.0138374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4860007036524934,"score_gpt":0.528739808086189,"score_spread":0.04273910443369561,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}