{"id":"W1591061497","doi":"10.3233/jad-2011-102094","title":"Regulation of Redox-Sensitive Signaling Pathways in Rat Primary Astrocytes Following Acrolein Exposure","year":2011,"lang":"en","type":"article","venue":"Journal of Alzheimer s Disease","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut National de la Recherche Scientifique","funders":"","keywords":"Acrolein; Chemistry; Glutathione; Lipid peroxidation; Biochemistry; Phosphorylation; Pharmacology; Oxidative stress; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001073677,0.0003373335,0.0002501348,0.0001909549,0.0001579745,0.0001567258,0.0001047928,0.0002186074,0.0009988334],"category_scores_gemma":[0.00006800875,0.000111252,0.0002903856,0.0002114248,0.0001527177,0.0001828256,0.0001330701,0.0004876414,0.0002476623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001103144,"about_ca_system_score_gemma":0.0001381711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006145727,"about_ca_topic_score_gemma":0.001268393,"domain_scores_codex":[0.9999104,0.00001094178,0.000008827589,0.00002078536,0.00002307652,0.00002594988],"domain_scores_gemma":[0.9999342,0.000006848124,0.00001956541,0.00000516749,0.00002018105,0.00001413811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000188719,0.00003008816,0.000118025,0.00004667614,0.000004561104,0.00006163495,0.00002503254,0.00002289803,0.9990394,0.00001901847,0.00002200827,0.0004218923],"study_design_scores_gemma":[0.00001435635,0.0005063275,0.005660601,0.000007142051,0.00001878098,0.0001234321,0.00007754691,0.0002346605,0.9923464,0.000065441,0.0009400884,0.000005223502],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902617,0.004212802,0.002937244,0.0001384027,0.00008953847,0.0000521565,0.0007303524,0.0000804845,0.001497314],"genre_scores_gemma":[0.9895064,0.002706122,0.003474216,0.0001141529,0.0000242485,0.0001322326,0.00068485,0.00001406908,0.003343617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009988334,"threshold_uncertainty_score":0.003341377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.023965841422142,"score_gpt":0.2426997942369482,"score_spread":0.2187339528148061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}