{"id":"W1591063089","doi":"10.1002/9780470697405.ch12","title":"Genetic and Therapeutic Control of Diabetogenic CD8 <sup>+</sup> T Cells","year":2008,"lang":"en","type":"article","venue":"Novartis Foundation symposium","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity; University of Calgary","funders":"","keywords":"NOD mice; Biology; Cytotoxic T cell; CD8; T cell; Insulitis; Immunology; T-cell receptor; IL-2 receptor; Epitope; Nod; Antigen; Cell biology; Immune system; Autoimmunity; Endocrinology; Diabetes mellitus; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001002877,0.0001430149,0.0001786018,0.00004538287,0.0001011565,0.00001880685,0.0001021922,0.0001197633,0.00006014574],"category_scores_gemma":[0.00001480716,0.0001442672,0.00008097158,0.0001057322,0.0001415683,0.000005838892,0.00003348557,0.00005112824,0.00002742327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001055971,"about_ca_system_score_gemma":0.00006308757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001805359,"about_ca_topic_score_gemma":0.000004033772,"domain_scores_codex":[0.9990316,0.00006285183,0.0002633092,0.0002702971,0.0001418203,0.0002301246],"domain_scores_gemma":[0.9994534,0.00001974097,0.0001265355,0.0002233266,0.0001136142,0.00006340259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003596915,0.00009832091,0.04543271,0.00001577352,0.0001472812,9.278869e-7,0.0001707907,0.0009384025,0.9492192,0.00005551647,0.0002667134,0.003618404],"study_design_scores_gemma":[0.009291775,0.001692352,0.07884993,0.00003957917,0.0003565654,0.00003687377,0.0002684716,0.01018479,0.8104779,0.000520242,0.08705221,0.001229269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960678,0.0007254754,0.002079762,0.0001990226,0.00007863698,0.0002011057,0.00001896766,0.00001321131,0.0006159673],"genre_scores_gemma":[0.9982715,0.0005212156,0.0001766546,0.000455594,0.00007949633,0.00001973602,0.00004754202,0.00002299276,0.0004052432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1387413,"threshold_uncertainty_score":0.5883046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007737609097957528,"score_gpt":0.2153861325421377,"score_spread":0.2076485234441802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}