{"id":"W1591119539","doi":"10.4049/jimmunol.174.7.4210","title":"Cross-Talk between CD14 and Complement Receptor 3 Promotes Phagocytosis of Mycobacteria: Regulation by Phosphatidylinositol 3-Kinase and Cytohesin-1","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; British Columbia Lung Association","keywords":"Cell biology; TLR2; Internalization; Phagocytosis; Biology; CD14; PI3K/AKT/mTOR pathway; Phosphatidylinositol; Signal transduction; Receptor; Molecular biology; Flow cytometry; TLR4; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016638,0.0002913012,0.0002234398,0.0001810393,0.0001861558,0.0002937619,0.0001987851,0.000396373,0.000948146],"category_scores_gemma":[0.0001426637,0.0001669125,0.0003749387,0.0001400062,0.0001965515,0.0002423576,0.0003039858,0.0005636009,0.0003764128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004655176,"about_ca_system_score_gemma":0.0002827219,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005522926,"about_ca_topic_score_gemma":0.0009141366,"domain_scores_codex":[0.9997872,0.00003964472,0.00001867582,0.0000322881,0.00004187074,0.00008043533],"domain_scores_gemma":[0.999905,0.00001363767,0.00002838651,0.000008335921,0.00001602836,0.00002864961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003675211,0.00003832266,0.000302873,0.00004236886,0.000004805906,0.00009308593,0.00001730918,0.00003209199,0.9982228,0.00009529595,0.0000393167,0.0007443001],"study_design_scores_gemma":[0.00007361631,0.0002749819,0.02969864,0.00001159768,0.00002577412,0.0003009514,0.00006951796,0.002875961,0.9651054,0.0001157385,0.001440294,0.000007577093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958398,0.001833473,0.001089208,0.0001551226,0.00003139501,0.00002376605,0.0001368225,0.000027835,0.0008625958],"genre_scores_gemma":[0.9957333,0.0008507415,0.00116203,0.0001256635,0.00001877816,0.0000593802,0.0002492263,0.000006859062,0.001794011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000948146,"threshold_uncertainty_score":0.003377557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014833453312399,"score_gpt":0.2489117852745659,"score_spread":0.2387634507414419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}