{"id":"W1591119539","doi":"10.4049/jimmunol.174.7.4210","title":"Cross-Talk between CD14 and Complement Receptor 3 Promotes Phagocytosis of Mycobacteria: Regulation by Phosphatidylinositol 3-Kinase and Cytohesin-1","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Research in Immunology and Cancer; Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; British Columbia Lung Association","keywords":"Cell biology; TLR2; Internalization; Phagocytosis; Biology; CD14; PI3K/AKT/mTOR pathway; Phosphatidylinositol; Signal transduction; Receptor; Molecular biology; Flow cytometry; TLR4; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009252648,0.0001575679,0.0004222054,0.0001162542,0.0002043528,0.0000177831,0.0001969788,0.0001934545,0.0003802471],"category_scores_gemma":[0.00009297028,0.0001112606,0.00005707237,0.00007615513,0.0004889274,0.0002630759,0.00009295819,0.0002190952,0.0000184515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004415012,"about_ca_system_score_gemma":0.00004398438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003485638,"about_ca_topic_score_gemma":0.000002432521,"domain_scores_codex":[0.9983302,0.0005089521,0.0007880502,0.0001042981,0.00005041954,0.0002180302],"domain_scores_gemma":[0.998398,0.0003820936,0.0008301314,0.0001840079,0.0001900397,0.00001574707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001186899,0.00005719772,0.003648299,0.00001543623,0.0003956433,4.202095e-7,0.000962278,0.000001437317,0.9618494,0.00007670498,0.000569521,0.0312368],"study_design_scores_gemma":[0.001955428,0.0007738632,0.08924213,0.00005486155,0.0001249697,0.0002146674,0.0002026062,0.000001957411,0.8851591,0.00006770863,0.02210475,0.00009798641],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810393,0.0171331,0.0001296152,0.001244126,0.00019682,0.0001947165,0.0000230608,0.000008806091,0.00003038879],"genre_scores_gemma":[0.9978123,0.001552322,0.0001919968,0.00003329556,0.00006385344,0.000002508774,0.00003989212,0.00001151782,0.000292292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08559383,"threshold_uncertainty_score":0.4537075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014833453312399,"score_gpt":0.2489117852745659,"score_spread":0.2387634507414419,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}