{"id":"W1591231244","doi":"10.1155/2010/218752","title":"Delivery of Exogenous Antigens to Induce Cytotoxic CD8+ T Lymphocyte Responses","year":2010,"lang":"en","type":"article","venue":"Journal of Biomedicine and Biotechnology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Dairy Farmers of Canada","keywords":"Cytotoxic T cell; Priming (agriculture); Cross-presentation; Major histocompatibility complex; Antigen; Immunology; Antigen presentation; MHC class I; Biology; CD8; Antigen processing; Immune system; T cell; Computational biology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007266211,0.0001915634,0.0006045371,0.001225097,0.0001153444,0.000005851254,0.0003842655,0.0007228322,0.0001432977],"category_scores_gemma":[0.0003321763,0.0001373596,0.0001088427,0.0004692626,0.0008862378,0.00007060671,0.0001094386,0.0006346394,0.00002652007],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002238676,"about_ca_system_score_gemma":0.0002482624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000613047,"about_ca_topic_score_gemma":0.00001125713,"domain_scores_codex":[0.9986005,0.0001261132,0.0007068358,0.0001756756,0.00006585757,0.0003249661],"domain_scores_gemma":[0.9987542,0.0002336397,0.0004531184,0.0003219366,0.0001965829,0.00004053215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002604902,0.0001347001,0.0005277042,0.00001501109,0.0001755135,0.00005493035,0.0003148656,5.055442e-8,0.9390665,0.0001090209,0.000556637,0.05644022],"study_design_scores_gemma":[0.002011184,0.003345163,0.005738203,0.00007961212,0.00005395521,0.004358622,0.0004348658,2.237849e-7,0.8924572,0.00004863934,0.09134302,0.0001292655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820437,0.01301306,0.00009429086,0.003508311,0.001133017,0.0001360201,0.0000164993,0.00002608694,0.00002897758],"genre_scores_gemma":[0.9949424,0.003656641,0.0005332002,0.0004185404,0.00006970484,0.000001635027,0.000002960668,0.00001493178,0.0003600223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09078638,"threshold_uncertainty_score":0.5601362,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051180035916042,"score_gpt":0.2469951168578022,"score_spread":0.2364833164986418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}