{"id":"W1591231244","doi":"10.1155/2010/218752","title":"Delivery of Exogenous Antigens to Induce Cytotoxic CD8+ T Lymphocyte Responses","year":2010,"lang":"en","type":"article","venue":"Journal of Biomedicine and Biotechnology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Dairy Farmers of Canada","keywords":"Cytotoxic T cell; Priming (agriculture); Cross-presentation; Major histocompatibility complex; Antigen; Immunology; Antigen presentation; MHC class I; Biology; CD8; Antigen processing; Immune system; T cell; Computational biology; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001683916,0.0003502143,0.0003155184,0.0002296507,0.00009882038,0.0004012981,0.0001091165,0.0004327717,0.001730114],"category_scores_gemma":[0.0001284475,0.0001199634,0.0002337687,0.0001545887,0.0001502098,0.0002853266,0.000275423,0.0006674465,0.0009335708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001454935,"about_ca_system_score_gemma":0.0001673667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006150756,"about_ca_topic_score_gemma":0.000103353,"domain_scores_codex":[0.9999031,0.00001911988,0.00001058277,0.00001671518,0.00002284449,0.00002759092],"domain_scores_gemma":[0.9999595,0.00001102666,0.00000969478,0.000006113867,0.000004978589,0.00000875979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006370141,0.00007210809,0.00008810846,0.0002097944,0.000007673433,0.00008898719,0.00001609725,0.0002383875,0.986833,0.0005026928,0.0001392827,0.01174022],"study_design_scores_gemma":[0.00005634147,0.001110727,0.0006566127,0.00003012421,0.00004205563,0.0003725462,0.00002604483,0.0009346671,0.9723308,0.0003985206,0.02403319,0.000008419037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8655802,0.03341093,0.0871931,0.001155078,0.0009297709,0.000511153,0.0005041864,0.0006678359,0.01004766],"genre_scores_gemma":[0.9462931,0.01594239,0.02699009,0.0004233161,0.0001787528,0.0001714063,0.0004471175,0.00007166951,0.00948213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001730114,"threshold_uncertainty_score":0.00578779,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01051180035916042,"score_gpt":0.2469951168578022,"score_spread":0.2364833164986418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}