{"id":"W159156586","doi":"10.1007/978-0-387-26575-9_5","title":"Synthesis and In Vitro Opioid Activity Profiles of Novel Cyclic Enkephalin Analogs","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Enkephalin; In vitro; Chemistry; Opioid; Pharmacology; Stereochemistry; Biochemistry; Biology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001532434,0.0003441018,0.0002231468,0.0001880316,0.0001588571,0.0003101852,0.0003225789,0.000231985,0.001482208],"category_scores_gemma":[0.0002326762,0.000164777,0.000216413,0.0001950899,0.0001960873,0.0003580318,0.0001594919,0.0005369462,0.0005003957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003278498,"about_ca_system_score_gemma":0.0001882268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005969594,"about_ca_topic_score_gemma":0.0009062717,"domain_scores_codex":[0.9999211,0.00001529202,0.0000105952,0.0000150356,0.00001824487,0.00001979242],"domain_scores_gemma":[0.9998966,0.00004186574,0.00001579316,0.00001167145,0.00001335482,0.00002071495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003189605,0.00004022105,0.00004270112,0.00005900323,0.000005008783,0.00008407126,0.00002387694,0.0005439247,0.9946714,0.0002925278,0.00005680653,0.003861477],"study_design_scores_gemma":[0.00001487543,0.0004703275,0.0004670064,0.000009849108,0.00001387153,0.0001719911,0.0000197173,0.0003277676,0.9950276,0.0001089039,0.003360207,0.000007860875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.957819,0.01904035,0.007896107,0.0001427018,0.00009321344,0.00009399506,0.00197138,0.00005697795,0.01288623],"genre_scores_gemma":[0.9649416,0.009901337,0.007660568,0.00009457942,0.00005479796,0.00007714387,0.003885598,0.00005086873,0.01333358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001482208,"threshold_uncertainty_score":0.00495851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03937482239226672,"score_gpt":0.2569091683211902,"score_spread":0.2175343459289234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}