{"id":"W1592449849","doi":"10.1038/bjp.2008.25","title":"Activation of ET<sub>B</sub>receptors regulates the abundance of ET‐1 mRNA in vascular endothelial cells","year":2008,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Biology; Cell biology; Chemistry; Molecular biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001605529,0.0001911734,0.0001800216,0.0001851444,0.0001265753,0.0003242995,0.0001110623,0.0002164571,0.001621034],"category_scores_gemma":[0.0001376162,0.0001300824,0.0001794303,0.0001292284,0.0001653932,0.0002340488,0.00009527481,0.0004462686,0.0006942506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002637139,"about_ca_system_score_gemma":0.000108999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003369592,"about_ca_topic_score_gemma":0.0002847171,"domain_scores_codex":[0.9998784,0.00002262825,0.00001177394,0.00002949237,0.00002712894,0.00003052817],"domain_scores_gemma":[0.999892,0.00002387145,0.00002779741,0.000009145152,0.00002508491,0.00002215341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009672529,0.00001267873,0.0001195645,0.00002960933,0.000002254872,0.00001850979,0.000005969666,0.000009912681,0.9991178,0.00002201079,0.00002673154,0.0005383425],"study_design_scores_gemma":[0.00004336545,0.0003901105,0.03767405,0.00002041015,0.00003142286,0.0005388532,0.00006706012,0.0009211315,0.9552105,0.000124776,0.004969279,0.000009032945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848029,0.008181773,0.003877812,0.0002455368,0.00007639174,0.00001952057,0.0005908041,0.00006977711,0.002135432],"genre_scores_gemma":[0.9864731,0.004791157,0.003755967,0.0001745675,0.00005825338,0.00008140214,0.001052604,0.0000323019,0.003580709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001621034,"threshold_uncertainty_score":0.00542289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01237255996921078,"score_gpt":0.2706573981922618,"score_spread":0.258284838223051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}