{"id":"W1592826781","doi":"10.1002/cncy.21535","title":"Multiplex sequencing for <i>EZH2</i>, <i>CD79B</i>, and <i>MYD88</i> mutations using archival cytospin preparations from B‐cell non‐Hodgkin lymphoma aspirates previously tested for <i>MYC</i> rearrangement and <i>IGH/BCL2</i> translocation","year":2015,"lang":"en","type":"article","venue":"Cancer Cytopathology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Chromosomal translocation; Sanger sequencing; Fluorescence in situ hybridization; Lymphoma; Gene rearrangement; Molecular biology; Multiplex; Multiplex ligation-dependent probe amplification; Multiplex polymerase chain reaction; Cancer research; Mutation; Biology; Medicine; Gene; Polymerase chain reaction; Genetics; Pathology; Chromosome; Exon","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020709,0.0003385049,0.0001787014,0.00087618,0.0002363827,0.0002963855,0.000233441,0.000307558,0.001537404],"category_scores_gemma":[0.0006454966,0.0001662279,0.0001492728,0.0003594733,0.0002396446,0.0001165427,0.0003903898,0.0002565454,0.0003639756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002608834,"about_ca_system_score_gemma":0.0001593553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009086537,"about_ca_topic_score_gemma":0.001308771,"domain_scores_codex":[0.999674,0.00002189822,0.00002637478,0.0001277849,0.000105649,0.00004433699],"domain_scores_gemma":[0.9997475,0.00006866609,0.00004147915,0.00004578041,0.00005999928,0.00003670961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004473047,0.00009030011,0.06329908,0.00007551032,0.00005237175,0.001165356,0.0004201799,0.0002703718,0.9113498,0.00009304729,0.0002805768,0.02245609],"study_design_scores_gemma":[0.0001074387,0.00084328,0.2479751,0.00003183835,0.0002214405,0.00863942,0.0004109019,0.00458732,0.7307832,0.0002409323,0.006137982,0.00002107361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931049,0.0002110736,0.004890182,0.00002577228,0.00000686091,0.0001312596,0.0005338794,0.00007741856,0.001018668],"genre_scores_gemma":[0.9844631,0.0003279875,0.0121539,0.00007584289,0.00001536065,0.0001934045,0.001466041,0.00002709626,0.001277189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001537404,"threshold_uncertainty_score":0.005143166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08855667975440545,"score_gpt":0.3405722976572889,"score_spread":0.2520156179028834,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}