{"id":"W1594559377","doi":"10.18433/j3630v","title":"Nanoparticle-Mediated Interleukin-12 Cancer Gene Therapy","year":2010,"lang":"en","type":"review","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gene delivery; Genetic enhancement; Immune system; Transfection; Systemic administration; DNA vaccination; In vivo; Naked DNA; Gene; Viral vector; Cancer research; Biology; Cytokine; Immunology; Genetics; Immunization","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000216592,0.000633981,0.0007954885,0.001048844,0.0001920291,0.0004972862,0.0006391177,0.0008743589,0.001569069],"category_scores_gemma":[0.000145481,0.0002306487,0.0002555348,0.0009132217,0.0003340842,0.0005745972,0.0003737707,0.0008388067,0.001775525],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006085255,"about_ca_system_score_gemma":0.0003246042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006097029,"about_ca_topic_score_gemma":0.0008253327,"domain_scores_codex":[0.9998977,0.00001439907,0.000006749878,0.00002100233,0.00004865876,0.00001147007],"domain_scores_gemma":[0.9999641,0.00001079106,0.000006952354,0.000001928373,0.00001190595,0.000004366484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008229333,0.0001865642,0.0001138614,0.007770221,0.00005691352,0.0004374048,0.00007373266,0.000921305,0.05323419,0.007018742,0.01825639,0.9118482],"study_design_scores_gemma":[0.00003670955,0.0002065514,0.0005099777,0.0006940578,0.00004324114,0.002292737,0.00003196549,0.0004888342,0.02851251,0.001509427,0.9656473,0.00002665275],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001495228,0.9910534,0.002205069,0.0002388182,0.0003949473,0.00002441876,0.00002162289,0.00004001193,0.004526412],"genre_scores_gemma":[0.008242637,0.9819598,0.002079518,0.0002290116,0.0001464817,0.00004574639,0.0000558478,0.000007071801,0.007233842],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001569069,"threshold_uncertainty_score":0.005249023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1695237023307867,"score_gpt":0.5014346873707306,"score_spread":0.3319109850399439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}