{"id":"W1595283544","doi":"10.4049/jimmunol.167.3.1728","title":"Autoantigen Glycoprotein 70 Expression Is Regulated by a Single Locus, Which Acts as a Checkpoint for Pathogenic Anti-Glycoprotein 70 Autoantibody Production and Hence for the Corresponding Development of Severe Nephritis, in Lupus-Prone BXSB Mice1","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Mary's Hospital Centre","funders":"","keywords":"Glycoprotein; Autoantibody; Locus (genetics); Immunology; Medicine; Biology; Cancer research; Gene; Molecular biology; Genetics; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759538,0.0005753033,0.0002502784,0.0006622699,0.0001880468,0.000366195,0.0002058631,0.0003174752,0.0008783223],"category_scores_gemma":[0.0001846724,0.0002638112,0.0002599311,0.00020227,0.0003549581,0.0001664665,0.0004184854,0.0006201279,0.0004018414],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002640772,"about_ca_system_score_gemma":0.0001320259,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000459309,"about_ca_topic_score_gemma":0.0007975271,"domain_scores_codex":[0.9997191,0.00004421354,0.00002418639,0.00007900474,0.00007856903,0.00005491901],"domain_scores_gemma":[0.9995692,0.00005200781,0.0002210797,0.00003469248,0.0000246354,0.00009829485],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004092538,0.000008017421,0.0004712265,0.000005356551,0.000001460361,0.00001839727,0.000008954014,0.00001537194,0.9991276,0.00002656427,0.000004919931,0.0002711722],"study_design_scores_gemma":[0.00003980427,0.0006556244,0.1336439,0.00003064122,0.00004952687,0.001782661,0.00008300561,0.0020367,0.859998,0.0002035064,0.001457223,0.00001951115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977115,0.0003578555,0.001387359,0.00002452292,0.000004069689,0.00000493071,0.0001482791,0.00003643017,0.0003250075],"genre_scores_gemma":[0.9952222,0.0004671463,0.002026086,0.00003487672,0.00001179537,0.00001877088,0.0006311309,0.00004093031,0.001547158],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008783223,"threshold_uncertainty_score":0.00293833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404416629587221,"score_gpt":0.2620518268531908,"score_spread":0.2480076605573186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}