{"id":"W1596092785","doi":"10.1016/s0140-6736(14)61704-9","title":"Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis","year":2015,"lang":"en","type":"review","venue":"The Lancet","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":636,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Cancer Institute; Agency for Healthcare Research and Quality; National Institutes of Health; Canadian Institutes of Health Research; University of Alabama at Birmingham; National Institute on Aging; Patient-Centered Outcomes Research Institute","keywords":"Medicine; Rheumatoid arthritis; Meta-analysis; Internal medicine; Odds ratio; MEDLINE; Relative risk; Clinical trial; Abatacept; Systematic review; Publication bias; Confidence interval; Rituximab","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008756134,0.0002596461,0.01086114,0.0001756344,0.00002185918,0.000008912113,0.00009545752,0.00008039527,0.00004904857],"category_scores_gemma":[0.0002155773,0.00009803151,0.0007107269,0.000553206,0.0001405828,0.00002635596,0.00002637769,0.0001385333,0.000004368879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004609306,"about_ca_system_score_gemma":0.0000740688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002670739,"about_ca_topic_score_gemma":0.0002127331,"domain_scores_codex":[0.9974983,0.001021385,0.000823477,0.0002046591,0.0002756176,0.0001765427],"domain_scores_gemma":[0.998243,0.0001936019,0.0007325781,0.0006200045,0.000146916,0.0000638425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.0001487137,0.0006362862,0.01120752,0.6858324,0.251201,0.00001149078,0.0002325126,7.221582e-7,1.420226e-8,0.00004150718,0.00007924804,0.05060854],"study_design_scores_gemma":[0.007296549,0.005873564,0.004633685,0.3104681,0.5865648,0.0001487176,0.00003264226,0.000003977854,6.203264e-7,0.0001316777,0.08426134,0.000584264],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002274964,0.9939714,0.000002106822,0.0000330167,0.00000461937,0.003348515,0.0003269321,0.00001068801,0.00002776709],"genre_scores_gemma":[0.001798494,0.9974145,0.00003606848,0.00001236824,0.000006295388,0.000588803,0.0001193132,0.00001313469,0.00001103516],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3753643,"threshold_uncertainty_score":0.7424459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08167305861819298,"score_gpt":0.3450265797049734,"score_spread":0.2633535210867804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}