{"id":"W1597122917","doi":"10.1158/1538-7445.am2014-909","title":"Abstract 909: Defining molecular and laboratory predictive biomarkers of response to cisplatin-based neoadjuvant chemotherapy (NC) in muscle-invasive bladder cancer (MIBC) - preliminary results and future plans","year":2014,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Bladder cancer; Cystectomy; Cisplatin; Oncology; Internal medicine; Chemotherapy; Cancer; Cohort; Gemcitabine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001813368,0.0005064867,0.0005801122,0.0005109512,0.0001311973,0.0008308585,0.0003734414,0.0003978426,0.001393447],"category_scores_gemma":[0.001984328,0.0001799316,0.0004399146,0.0005385887,0.0002857333,0.0004290224,0.0002913053,0.0004660817,0.0005167883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003475464,"about_ca_system_score_gemma":0.0004004217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005185288,"about_ca_topic_score_gemma":0.0004207252,"domain_scores_codex":[0.999521,0.0002141908,0.00005033264,0.00008852444,0.00008425948,0.00004180374],"domain_scores_gemma":[0.9991048,0.0003372568,0.0002046312,0.00005584089,0.0001840606,0.0001134791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0168784,0.001262079,0.7630582,0.0009516705,0.0004572451,0.0003726159,0.0001851232,0.001702988,0.08290727,0.0001519132,0.001778144,0.1302943],"study_design_scores_gemma":[0.0003404339,0.01195341,0.9512125,0.0001254837,0.0005659723,0.00121569,0.0002494591,0.005155134,0.02415921,0.0002204471,0.004761047,0.00004125265],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713684,0.02109187,0.003431901,0.0005604399,0.00009520243,0.0003113392,0.001450094,0.0000913377,0.001599501],"genre_scores_gemma":[0.9901958,0.002381605,0.004037614,0.0001867128,0.0001265544,0.0002235803,0.002060354,0.00001414712,0.0007736457],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001813368,"threshold_uncertainty_score":0.009590089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02193102164403776,"score_gpt":0.347405954096813,"score_spread":0.3254749324527752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}