{"id":"W1597707147","doi":"10.1111/j.1460-9568.2007.05807.x","title":"Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats","year":2007,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Tekes","keywords":"Neuroprotection; Morris water navigation task; Hippocampus; Genetically modified mouse; Ischemia; Medicine; Middle cerebral artery; Neuroscience; Neuroplasticity; Amyloid precursor protein; Cerebral cortex; Transgene; Lesion; Water maze; Internal medicine; Anesthesia; Pathology; Psychology; Chemistry; Alzheimer's disease; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003200071,0.001076136,0.000798014,0.0008702605,0.0002977205,0.0004325707,0.0004040917,0.0005592177,0.001247286],"category_scores_gemma":[0.0003039099,0.0004266451,0.0004820224,0.0003132567,0.0008191437,0.0006671234,0.0003644374,0.001109021,0.0004906939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003144404,"about_ca_system_score_gemma":0.0004522079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001135468,"about_ca_topic_score_gemma":0.00185837,"domain_scores_codex":[0.9997283,0.0000370944,0.00003405162,0.00004927405,0.00004452903,0.0001066926],"domain_scores_gemma":[0.9995602,0.0000355249,0.0001510121,0.00006790279,0.0000323461,0.0001530788],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003350775,0.0006713589,0.0003915673,0.00009610441,0.00003495497,0.0003114864,0.00007538676,0.00009554112,0.990451,0.0001531863,0.0001176536,0.00425111],"study_design_scores_gemma":[0.0003774503,0.01684249,0.01189583,0.0000453984,0.000199094,0.0008970412,0.0001875802,0.0008936902,0.9664705,0.0003859832,0.001766847,0.00003818924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980419,0.0007530335,0.0004486139,0.00009457112,0.00003296554,0.00001459554,0.0001268292,0.00007923196,0.0004081794],"genre_scores_gemma":[0.9946536,0.001720517,0.001212509,0.00006970352,0.00003942897,0.00005564562,0.0003974116,0.00002913808,0.001821943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001247286,"threshold_uncertainty_score":0.004172564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04870685743291413,"score_gpt":0.2904002593001049,"score_spread":0.2416934018671908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}