{"id":"W1598062630","doi":"10.4049/jimmunol.176.4.2635","title":"Tolerance Induction by Transcutaneous Immunization through Ultraviolet-Irradiated Skin Is Transferable through CD4+CD25+ T Regulatory Cells and Is Dependent on Host-Derived IL-10","year":2006,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's & Women's Health Centre of British Columbia","funders":"","keywords":"CTL*; Immune tolerance; Priming (agriculture); Immune system; Immunology; Adjuvant; Adoptive cell transfer; Immunization; Hapten; Biology; MHC class I; Antigen; T cell; Major histocompatibility complex; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001343603,0.0005598406,0.0002728628,0.0002119147,0.00008386694,0.0002324646,0.0001990085,0.0002662945,0.001292931],"category_scores_gemma":[0.0001024683,0.0001560271,0.0002990827,0.00008483943,0.0002610073,0.0001809047,0.0001362186,0.0006380484,0.0002689399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000140305,"about_ca_system_score_gemma":0.0001612775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001857838,"about_ca_topic_score_gemma":0.0002348024,"domain_scores_codex":[0.9998617,0.000019095,0.0000106953,0.00002955216,0.00003824892,0.00004063658],"domain_scores_gemma":[0.999908,0.00001749091,0.00003243805,0.0000156506,0.000008137285,0.00001832822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005838034,0.0000606678,0.0001123596,0.00002426366,0.000003665809,0.00003479771,0.000006379089,0.00003530541,0.9985943,0.00002981554,0.00001253022,0.001027486],"study_design_scores_gemma":[0.00001379628,0.001145946,0.002276781,0.000006267792,0.00001876643,0.000274859,0.00001126649,0.0003074347,0.9952478,0.00002640743,0.0006679253,0.000002862034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935039,0.0009301138,0.003828518,0.00003442112,0.00003925531,0.00006277001,0.00007926849,0.000148297,0.001373577],"genre_scores_gemma":[0.9945284,0.0009169873,0.002319698,0.00004141764,0.00001510561,0.00007049691,0.0001772167,0.00001687176,0.001913808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001292931,"threshold_uncertainty_score":0.00432533,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007119197454110792,"score_gpt":0.1999861922659212,"score_spread":0.1928669948118104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}