{"id":"W1599091078","doi":"10.1002/9781118775882.ch2","title":"Bioconjugates Based on Poly(Ethylene Glycol)s and Polyglycerols","year":2014,"lang":"en","type":"other","venue":"","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ethylene glycol; PEGylation; Polyethylene glycol; Immunogenicity; Dispersity; PEG ratio; Gene delivery; Polymer; Drug delivery; Chemistry; Combinatorial chemistry; Genetic enhancement; Polymerization; Biophysics; Nanotechnology; Materials science; Polymer chemistry; Biochemistry; Organic chemistry; Biology; Immune system; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007925268,0.0005549415,0.0001676136,0.0003445166,0.0001171036,0.0003222291,0.0001671895,0.0002514482,0.001817131],"category_scores_gemma":[0.00006409593,0.0001417802,0.0002384137,0.0003545464,0.0001622644,0.0002689422,0.0002207924,0.0002366948,0.001316503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002392252,"about_ca_system_score_gemma":0.0001616547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004042938,"about_ca_topic_score_gemma":0.0005381474,"domain_scores_codex":[0.9999366,0.000006762124,0.000005625224,0.00001215794,0.00002286544,0.00001597223],"domain_scores_gemma":[0.9999855,0.000002210511,0.000004144657,0.000001383733,0.000003024288,0.000003781081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005672493,0.00002689953,0.0001210098,0.0002994811,0.0000100297,0.0002580704,0.00002991641,0.0003440402,0.9375528,0.002685376,0.0006117454,0.05800381],"study_design_scores_gemma":[0.000007779557,0.0001590198,0.0007839534,0.00003897896,0.00002727124,0.0006673998,0.000017093,0.0004119986,0.9146305,0.0002841604,0.08296036,0.0000114741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6893256,0.1209213,0.07794965,0.0008476896,0.0006926398,0.0002816658,0.0004980445,0.001606637,0.1078767],"genre_scores_gemma":[0.7392995,0.1116721,0.04746505,0.0007058755,0.0001201614,0.000192189,0.000708434,0.0002493571,0.0995874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001817131,"threshold_uncertainty_score":0.006078959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005464659801819851,"score_gpt":0.2246602106345002,"score_spread":0.2191955508326804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}