{"id":"W1599217375","doi":"10.1186/s12891-015-0605-3","title":"Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide","year":2015,"lang":"en","type":"article","venue":"BMC Musculoskeletal Disorders","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"Universidad de Caldas; Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Synovial membrane; Lipopolysaccharide; Synovitis; Cytokine; Synovial fluid; Tumor necrosis factor alpha; Medicine; Platelet; Interleukin; Immunology; Growth factor; Platelet-derived growth factor; Internal medicine; Inflammation; Endocrinology; Osteoarthritis; Molecular biology; Platelet-derived growth factor receptor; Biology; Receptor; Pathology; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000810394,0.0002847196,0.0004155488,0.0001604259,0.00005027027,0.00001627436,0.00007350152,0.00008721302,0.00007922864],"category_scores_gemma":[0.00009459788,0.0002195541,0.00008389338,0.0001319588,0.0001324185,0.0002160168,0.00003174303,0.0001472355,0.00002621316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008238465,"about_ca_system_score_gemma":0.0001565572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006931276,"about_ca_topic_score_gemma":0.002771792,"domain_scores_codex":[0.9985185,0.00008568659,0.0002732312,0.0003549074,0.000457201,0.0003104248],"domain_scores_gemma":[0.9993308,0.00008881817,0.00008107162,0.0001810818,0.00004951477,0.0002687034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005949972,0.003862577,0.8672282,0.001059864,0.0006056259,0.0002844622,0.00290811,0.000149347,0.1055893,0.00206253,0.00007123782,0.01022876],"study_design_scores_gemma":[0.03861838,0.004051433,0.9087386,0.0003643681,0.0001544173,0.00006365226,0.0002473551,0.001762648,0.04534803,0.00005050711,0.00006249827,0.0005381451],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977717,0.0002032199,0.0000438058,0.00007890657,0.0000749983,0.0007295798,0.00007177658,0.00004099872,0.0009850409],"genre_scores_gemma":[0.9992853,0.0001047417,0.0001472429,0.00007392348,0.00004434315,0.00004758986,0.0001462798,0.00003303414,0.0001174994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06024127,"threshold_uncertainty_score":0.8953155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562777933269788,"score_gpt":0.2683728161250935,"score_spread":0.2527450367923956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}