{"id":"W1599217375","doi":"10.1186/s12891-015-0605-3","title":"Effects over time of two platelet gel supernatants on growth factor, cytokine and hyaluronan concentrations in normal synovial membrane explants challenged with lipopolysaccharide","year":2015,"lang":"en","type":"article","venue":"BMC Musculoskeletal Disorders","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"Universidad de Caldas; Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Synovial membrane; Lipopolysaccharide; Synovitis; Cytokine; Synovial fluid; Tumor necrosis factor alpha; Medicine; Platelet; Interleukin; Immunology; Growth factor; Platelet-derived growth factor; Internal medicine; Inflammation; Endocrinology; Osteoarthritis; Molecular biology; Platelet-derived growth factor receptor; Biology; Receptor; Pathology; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002865504,0.0004096762,0.0003460231,0.0002112014,0.0001155264,0.0003528444,0.0001240522,0.0003011232,0.001309099],"category_scores_gemma":[0.0002746528,0.000151983,0.0002940942,0.0001610211,0.0002484335,0.0003046496,0.0001776111,0.0005892619,0.0003042418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001626847,"about_ca_system_score_gemma":0.0001746917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003030404,"about_ca_topic_score_gemma":0.0005800461,"domain_scores_codex":[0.9997566,0.00005370795,0.00003188564,0.00004009759,0.00006351682,0.00005410292],"domain_scores_gemma":[0.9996608,0.0001006393,0.00008077415,0.00003095263,0.00007105014,0.00005578029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001345731,0.000121911,0.0005137717,0.0001013196,0.00001032781,0.0001071411,0.0001028973,0.00004825471,0.9962053,0.00001865459,0.00002913999,0.001395555],"study_design_scores_gemma":[0.00002897179,0.004659649,0.01205831,0.00002150985,0.00004302284,0.0001873226,0.0002353976,0.0004052547,0.9811974,0.00002888841,0.001120892,0.00001334329],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965475,0.001829037,0.0006396411,0.00005737296,0.00004315114,0.00003244805,0.0002230642,0.00001385717,0.0006139225],"genre_scores_gemma":[0.9950652,0.001072932,0.00162911,0.00006577919,0.0000263376,0.0001026536,0.0003939366,0.000007570513,0.001636444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001309099,"threshold_uncertainty_score":0.004379392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562777933269788,"score_gpt":0.2683728161250935,"score_spread":0.2527450367923956,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}