{"id":"W1599242518","doi":"10.1111/j.1398-9995.2011.02590.x","title":"How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA2LEN statement","year":2011,"lang":"en","type":"review","venue":"Allergy","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; McMaster University","funders":"","keywords":"Medicine; Randomized controlled trial; Allergy; Placebo; Allergen immunotherapy; Internal medicine; Immunotherapy; Clinical trial; Allergen; Physical therapy; Alternative medicine; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":["metaresearch"],"category_scores_codex":[0.7057226,0.006331132,0.01978173,0.0104042,0.004123841,0.01665063,0.008075731,0.03383728,0.01501661],"category_scores_gemma":[0.8052291,0.007783239,0.02215986,0.009254997,0.009372731,0.01219628,0.00768544,0.02575335,0.01550021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009677453,"about_ca_system_score_gemma":0.02413859,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00231235,"about_ca_topic_score_gemma":0.002861903,"domain_scores_codex":[0.1664059,0.7030765,0.08284494,0.0104086,0.03466816,0.002595896],"domain_scores_gemma":[0.1148886,0.6798548,0.04944413,0.06095215,0.08508879,0.009771615],"domain_codex":"methods","domain_gemma":"methods","domain_candidate":"methods","domain_consensus":"methods","study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02032517,0.0009772247,0.002862562,0.06873489,0.02178833,0.0006259679,0.001694599,0.008074055,0.00256924,0.06453948,0.4169367,0.3908718],"study_design_scores_gemma":[0.0566343,0.003621083,0.00416635,0.07956361,0.0108465,0.000654866,0.0004541342,0.03160544,0.003636632,0.1496374,0.6580345,0.001145211],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.002213494,0.03790412,0.3582461,0.266002,0.1448317,0.1620263,0.007263077,0.006230541,0.01528257],"genre_scores_gemma":[0.0114268,0.005621632,0.6923226,0.09214343,0.01932971,0.1729923,0.001386123,0.00097851,0.003798976],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2942774,"threshold_uncertainty_score":0.3628964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1559100064931625,"score_gpt":0.3887975371613456,"score_spread":0.232887530668183,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}