{"id":"W1599542080","doi":"10.1038/gene.2015.17","title":"Suppression of autoimmunity by CD5+ IL-10-producing B cells in lupus-prone mice","year":2015,"lang":"en","type":"article","venue":"Genes and Immunity","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":false,"ca_institutions":"William Osler Health System; Mount Sinai Hospital; Toronto Western Hospital; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"CD5; Biology; Systemic lupus erythematosus; Adoptive cell transfer; Immunology; Autoimmunity; Natural killer T cell; Autoantibody; Population; Antibody; Molecular biology; Immune system; T cell; Internal medicine; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006097025,0.0001658214,0.0002905443,0.0001150302,0.0001586603,0.00001379898,0.0001735409,0.0002033908,0.0004873297],"category_scores_gemma":[0.00007396745,0.000149325,0.00005007717,0.0001446028,0.0001567135,0.0002037374,0.0001886854,0.0003972684,0.0001117868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004608241,"about_ca_system_score_gemma":0.00004717875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003449327,"about_ca_topic_score_gemma":0.00002917901,"domain_scores_codex":[0.9986904,0.0004486574,0.000373337,0.0002052711,0.00003940022,0.000242992],"domain_scores_gemma":[0.9992254,0.00007340705,0.000160334,0.0003844713,0.0001308999,0.00002550408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003931947,0.0002151239,0.001038157,0.00003224301,0.00003049473,3.604554e-7,0.001266155,0.00001072136,0.9581183,0.000009441654,0.03281293,0.006072866],"study_design_scores_gemma":[0.001364034,0.0002700819,0.003462683,0.00005871535,0.00001766906,0.00002868241,0.002246034,0.00002953785,0.7881333,0.00002251181,0.2042059,0.000160843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853456,0.009979047,0.00005749431,0.00008434947,0.002896893,0.0001625878,0.0000196651,0.00003282924,0.001421548],"genre_scores_gemma":[0.9800003,0.000714656,0.00004240353,0.00006182776,0.00001344549,0.000008210169,0.0002777343,0.00001342059,0.01886801],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.171393,"threshold_uncertainty_score":0.6089296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02009926244435615,"score_gpt":0.2386650979938854,"score_spread":0.2185658355495293,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}