{"id":"W1600230194","doi":"10.1002/cncr.29363","title":"Phase 2 study of <scp>MK</scp>‐2206, an allosteric inhibitor of <scp>AKT</scp>, as second‐line therapy for advanced gastric and gastroesophageal junction cancer: A SWOG cooperative group trial (<scp>S</scp>1005)","year":2015,"lang":"en","type":"article","venue":"Cancer","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Medicine; Gastroenterology; Internal medicine; Rash; Adverse effect; Nausea; Vomiting; Clinical endpoint; Anemia; Cancer; Diarrhea; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001554444,0.001432078,0.001256094,0.0004325346,0.000283944,0.0006189611,0.0007097691,0.0009226007,0.003623014],"category_scores_gemma":[0.0005300647,0.000414871,0.00102582,0.0003600746,0.0005729606,0.0004034706,0.0002641981,0.002047486,0.000594962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006540256,"about_ca_system_score_gemma":0.001644543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001195366,"about_ca_topic_score_gemma":0.003245499,"domain_scores_codex":[0.9997408,0.0001330914,0.00001065871,0.00003259038,0.00002862197,0.00005426732],"domain_scores_gemma":[0.9995652,0.0000658097,0.00009054092,0.00002958893,0.00003322201,0.0002155997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.712082,0.0883267,0.01115354,0.001471732,0.001825455,0.0005274429,0.0004023073,0.003953487,0.07200083,0.000399807,0.007988461,0.09986824],"study_design_scores_gemma":[0.6946093,0.2831132,0.01199371,0.0000460244,0.0005297814,0.0003784965,0.00004465886,0.001534702,0.004904431,0.000126771,0.002696231,0.00002271888],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934338,0.001249078,0.0004334588,0.0003161534,0.00007344657,0.002306072,0.0009451805,0.00006715053,0.001175595],"genre_scores_gemma":[0.9840657,0.002085577,0.002224284,0.0008469332,0.0001656409,0.003781495,0.003531838,0.00003304219,0.003265421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003623014,"threshold_uncertainty_score":0.01212019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04130629297028603,"score_gpt":0.341440078508031,"score_spread":0.3001337855377449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}