{"id":"W1600230194","doi":"10.1002/cncr.29363","title":"Phase 2 study of <scp>MK</scp>‐2206, an allosteric inhibitor of <scp>AKT</scp>, as second‐line therapy for advanced gastric and gastroesophageal junction cancer: A SWOG cooperative group trial (<scp>S</scp>1005)","year":2015,"lang":"en","type":"article","venue":"Cancer","topic":"Gastric Cancer Management and Outcomes","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"Medicine; Gastroenterology; Internal medicine; Rash; Adverse effect; Nausea; Vomiting; Clinical endpoint; Anemia; Cancer; Diarrhea; Surgery; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006536751,0.0006860152,0.001542944,0.0006248415,0.0001527625,0.00006753181,0.0002926732,0.0001932479,0.00005694659],"category_scores_gemma":[0.0005868354,0.0005913416,0.0002459947,0.001163115,0.0002169988,0.000584867,0.0001314188,0.0003810603,0.000003609533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004357261,"about_ca_system_score_gemma":0.0006008692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003843594,"about_ca_topic_score_gemma":0.0005371576,"domain_scores_codex":[0.9959821,0.0002028919,0.001145282,0.0009917269,0.0008357559,0.000842313],"domain_scores_gemma":[0.9966231,0.0005198071,0.0009129655,0.0006072697,0.0007522713,0.0005845792],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.07787508,0.03745992,0.1388675,0.003565878,0.009052109,0.0003867149,0.06890242,0.003025449,0.1111671,0.0002446315,0.21313,0.3363233],"study_design_scores_gemma":[0.6764725,0.1317092,0.01895816,0.0005155582,0.002405385,0.00004550006,0.04505957,0.001441203,0.03542824,0.0001050786,0.08756213,0.0002975097],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984232,0.006063882,0.0005898041,0.00007056257,0.002121423,0.006086775,0.0002667553,0.0001065004,0.0004623072],"genre_scores_gemma":[0.9875959,0.001225607,0.0004637818,0.0005824695,0.002057912,0.001775192,0.0001909701,0.0001226496,0.005985545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5985974,"threshold_uncertainty_score":0.9996538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04130629297028603,"score_gpt":0.341440078508031,"score_spread":0.3001337855377449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}