{"id":"W1601758486","doi":"10.1111/j.1750-3639.2012.00633.x","title":"<scp>A</scp>urora Kinase <scp>B</scp> Is a Potential Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma","year":2012,"lang":"en","type":"article","venue":"Brain Pathology","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; National Brain Tumor Society","keywords":"Cancer research; Pons; Immunohistochemistry; Glioma; Medicine; Cell cycle; Pathology; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008754398,0.0002074617,0.0002172557,0.000296227,0.0001784526,0.0003099576,0.0001110194,0.0001659231,0.0006110778],"category_scores_gemma":[0.00009894107,0.0000886081,0.0001065778,0.0003982085,0.0001938272,0.0001615661,0.0001390035,0.0002955153,0.000201784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002665869,"about_ca_system_score_gemma":0.000348767,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001080788,"about_ca_topic_score_gemma":0.002026163,"domain_scores_codex":[0.999927,0.000008925545,0.00000472184,0.00001721586,0.00002319855,0.00001877496],"domain_scores_gemma":[0.9999565,0.000005853855,0.00001789895,0.00000357983,0.000006204131,0.000009985281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004251518,0.00005245937,0.01198514,0.000163134,0.000026433,0.0004678441,0.00004214895,0.0005781639,0.9615073,0.0001798236,0.0004543575,0.02411806],"study_design_scores_gemma":[0.00005235012,0.001490191,0.2018536,0.00003350976,0.00009192149,0.005834956,0.0002393493,0.002756012,0.7663326,0.0002839104,0.0210184,0.00001311771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888853,0.007128526,0.001546465,0.000169025,0.000009751562,0.00003692897,0.0004947289,0.00006183,0.001667427],"genre_scores_gemma":[0.9922749,0.005002671,0.001380768,0.00005400845,0.000009422803,0.00003496438,0.000668903,0.00001200284,0.0005622112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001080788,"threshold_uncertainty_score":0.002149045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006947306415567666,"score_gpt":0.2274909681762478,"score_spread":0.2205436617606801,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}