{"id":"W1602770001","doi":"10.1089/chi.2014.0128","title":"Deletion of the MC4R Gene in a 9-Year-Old Obese Boy","year":2015,"lang":"en","type":"article","venue":"Childhood Obesity","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; Memorial University of Newfoundland","funders":"","keywords":"Genetics; Haploinsufficiency; Gene duplication; Biology; Melanocortin 4 receptor; Gene; Missense mutation; Obesity; Copy-number variation; Mutation; Endocrinology; Phenotype; Melanocortin; Genome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002913998,0.001968252,0.001146023,0.002122115,0.002713596,0.0009677846,0.0009897437,0.002859079,0.002489099],"category_scores_gemma":[0.001297154,0.001165141,0.0007759591,0.001044522,0.001309181,0.0009766462,0.001272146,0.002824243,0.00078597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006635987,"about_ca_system_score_gemma":0.0008161631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00275957,"about_ca_topic_score_gemma":0.002748647,"domain_scores_codex":[0.9995518,0.00003824103,0.00003668087,0.0001511529,0.00009231355,0.0001297289],"domain_scores_gemma":[0.9991136,0.0002284983,0.0001586301,0.00003296084,0.00005384701,0.0004124164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00006167595,0.0001157797,0.01038278,0.00003436835,0.000009467319,0.9841064,0.0003901069,0.00006401307,0.002930054,0.0001318957,0.0002947914,0.001478746],"study_design_scores_gemma":[0.00001968756,0.0002524329,0.02784551,0.00002410799,0.00002097073,0.9696382,0.0002384874,0.0001726865,0.0007581105,0.00008312449,0.0009274838,0.00001915144],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993434,0.001129912,0.0007118983,0.001341517,0.0001675084,0.00006128463,0.0003521918,0.00007477358,0.002727036],"genre_scores_gemma":[0.9962364,0.0007817762,0.0008085864,0.0004352256,0.0001985798,0.0000263172,0.0001570253,0.00002741304,0.001328677],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002859079,"threshold_uncertainty_score":0.008326828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02321143003415707,"score_gpt":0.2356321422190648,"score_spread":0.2124207121849077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}