{"id":"W1602810241","doi":"","title":"Colon cancer chemopreventive properties of β-Escin, a triterpene saponin constituent of Aesculus hippocastanum","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Azoxymethane; Aberrant crypt foci; Medicine; Traditional medicine; Aesculus hippocastanum; Apoptosis; Limonin; Colorectal cancer; Perilla; Cancer; Pharmacology; Internal medicine; Chemistry; Food science; Botany; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006432341,0.0003315557,0.0001448671,0.0003405386,0.00007995378,0.00008685581,0.00006536396,0.00009577462,0.0009532846],"category_scores_gemma":[0.00004503072,0.00006278978,0.0001365182,0.0001408625,0.0001062693,0.00007200836,0.00006527619,0.0002001936,0.0001120849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001131262,"about_ca_system_score_gemma":0.0001817874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007391967,"about_ca_topic_score_gemma":0.001755201,"domain_scores_codex":[0.9999737,0.000005594066,0.000002301822,0.000003239963,0.000007569991,0.000007611457],"domain_scores_gemma":[0.999963,0.000004884361,0.000009249197,0.000003725321,0.000005839117,0.0000132234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000163872,0.00004527022,0.0002380431,0.00003120478,0.000005186003,0.00002516463,0.000004453843,0.00003254553,0.9979249,0.0000214497,0.00001313842,0.001494626],"study_design_scores_gemma":[0.00002618419,0.001065649,0.01514506,0.000007699605,0.00002860246,0.0001072975,0.00001500006,0.0002243028,0.9821671,0.00001496556,0.001196027,0.000002112875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974771,0.001114842,0.0003144427,0.00003500385,0.000006832599,0.00001707452,0.0002101609,0.00002288122,0.0008017288],"genre_scores_gemma":[0.9954643,0.001380755,0.0007127317,0.00002486039,0.000005627465,0.00001396519,0.0003993245,0.000005830503,0.001992638],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009532846,"threshold_uncertainty_score":0.003189087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06193321961214754,"score_gpt":0.3662948354223552,"score_spread":0.3043616158102077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}