{"id":"W1602986529","doi":"10.4049/jimmunol.182.1.193","title":"CD4+ Th-APC with Acquired Peptide/MHC Class I and II Complexes Stimulate Type 1 Helper CD4+ and Central Memory CD8+ T Cell Responses","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD80; T cell; Biology; CD8; Cytotoxic T cell; Priming (agriculture); CTL*; Antigen-presenting cell; Cell biology; Immunology; MHC class I; CD40; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007406026,0.0003704246,0.0007074078,0.0002551822,0.0006905569,0.0000355922,0.000480814,0.0003159335,0.0002744679],"category_scores_gemma":[0.0001465917,0.0002259984,0.0001006656,0.0001848529,0.001222852,0.0002564662,0.0001393771,0.0006559866,0.00002771203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004747143,"about_ca_system_score_gemma":0.0001937514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004960825,"about_ca_topic_score_gemma":0.000008528534,"domain_scores_codex":[0.9970844,0.00131008,0.0006504537,0.0002180366,0.00007926354,0.0006577445],"domain_scores_gemma":[0.9978422,0.000921168,0.0005446305,0.0004267489,0.00022607,0.00003918527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0320886,0.0002105386,0.0003335213,0.000009362025,0.0006057154,0.00003305671,0.003890158,0.00002509218,0.9564398,0.0001454789,0.001055506,0.005163193],"study_design_scores_gemma":[0.01832663,0.0279201,0.2592712,0.0003589129,0.0007696665,0.017875,0.006758322,0.00001414891,0.5953271,0.0007622703,0.07156674,0.001049892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9145699,0.08219472,0.00003490518,0.002117498,0.0005751878,0.0002002083,0.000009523364,0.00003071201,0.0002673086],"genre_scores_gemma":[0.9863499,0.008196392,0.0001132119,0.0006916361,0.00005095776,0.000001250519,0.000006972045,0.00002913523,0.004560576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3611127,"threshold_uncertainty_score":0.9215947,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0117220544015327,"score_gpt":0.2329603055052039,"score_spread":0.2212382511036712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}