{"id":"W1602986529","doi":"10.4049/jimmunol.182.1.193","title":"CD4+ Th-APC with Acquired Peptide/MHC Class I and II Complexes Stimulate Type 1 Helper CD4+ and Central Memory CD8+ T Cell Responses","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"","keywords":"CD80; T cell; Biology; CD8; Cytotoxic T cell; Priming (agriculture); CTL*; Antigen-presenting cell; Cell biology; Immunology; MHC class I; CD40; Immune system; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001112774,0.0005606779,0.0003130429,0.0001713915,0.0001148712,0.0003145951,0.0001294302,0.0002803681,0.003865137],"category_scores_gemma":[0.0001079801,0.0001297472,0.0002896603,0.00009011301,0.0001441338,0.0001909149,0.0002327372,0.0005983379,0.001271617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002097899,"about_ca_system_score_gemma":0.0002181376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000153918,"about_ca_topic_score_gemma":0.0003196683,"domain_scores_codex":[0.9998482,0.00002405645,0.00000801938,0.00002596211,0.0000311013,0.00006266515],"domain_scores_gemma":[0.9999242,0.000009843572,0.00001353029,0.00000807705,0.00001054881,0.00003377514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001463626,0.00007650826,0.0006894943,0.00009333712,0.000007883536,0.0001072408,0.00002408369,0.00008674459,0.9935327,0.00009334753,0.0001636706,0.004978583],"study_design_scores_gemma":[0.0001804158,0.003344531,0.01544081,0.00007811172,0.000111081,0.001178018,0.0001624223,0.003326922,0.9637347,0.0005552191,0.01187568,0.00001213087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895448,0.002524989,0.002689647,0.0001369389,0.0001119967,0.00007144926,0.0001211059,0.0001497377,0.004649341],"genre_scores_gemma":[0.9869891,0.00110756,0.002549511,0.0001918129,0.0001376794,0.00008483971,0.0003432521,0.00002928335,0.008566947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003865137,"threshold_uncertainty_score":0.0129301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0117220544015327,"score_gpt":0.2329603055052039,"score_spread":0.2212382511036712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}