{"id":"W1603054107","doi":"10.4049/jimmunol.179.4.2339","title":"CTLs Contain and Use Intracellular Stores of FasL Distinct from Cytolytic Granules","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Division of Chemistry","keywords":"Cytolysis; Intracellular; Fas ligand; Cell biology; Biology; Chemistry; Virology; Cytotoxic T cell; Biochemistry; Apoptosis; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004907169,0.00009098563,0.0001898082,0.00004310702,0.00004230257,0.00000553008,0.0001580672,0.0001165401,0.00001638168],"category_scores_gemma":[0.00006903513,0.00006203744,0.00007163025,0.00003262324,0.0002559021,0.000005726699,0.00002934452,0.0001459354,6.421902e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007471466,"about_ca_system_score_gemma":0.00002811352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001411159,"about_ca_topic_score_gemma":0.0001660701,"domain_scores_codex":[0.9992812,0.00008683369,0.0003495342,0.00007187244,0.00007929216,0.000131212],"domain_scores_gemma":[0.9993564,0.00008705225,0.0002631887,0.000166294,0.00009649571,0.00003051129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009166832,0.0000326304,0.01350374,0.000004221713,0.0001520651,0.00001660217,0.0002630593,0.000003745317,0.983496,0.00008458529,0.000009634499,0.001517046],"study_design_scores_gemma":[0.001119394,0.0007608064,0.1850951,0.00002979987,0.0001487916,0.0001465031,0.0006815124,0.000008724776,0.8056225,0.000443105,0.005830406,0.0001133868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668949,0.01246412,0.02035684,0.00007285293,0.0001266836,0.00005289188,0.000009245724,0.000001570142,0.00002094052],"genre_scores_gemma":[0.9983693,0.001197122,0.0001732197,0.00002619051,0.0001076102,1.883262e-7,0.00007475619,0.000008671506,0.00004291642],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1778735,"threshold_uncertainty_score":0.2529813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00804700068547337,"score_gpt":0.2131010666906388,"score_spread":0.2050540660051654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}