{"id":"W1603054107","doi":"10.4049/jimmunol.179.4.2339","title":"CTLs Contain and Use Intracellular Stores of FasL Distinct from Cytolytic Granules","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Division of Chemistry","keywords":"Cytolysis; Intracellular; Fas ligand; Cell biology; Biology; Chemistry; Virology; Cytotoxic T cell; Biochemistry; Apoptosis; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001282139,0.0002766731,0.0002191813,0.0001771646,0.0001416951,0.0006858635,0.0001928843,0.0004028964,0.0008189147],"category_scores_gemma":[0.000194341,0.0001194342,0.0002220242,0.0001357611,0.000248452,0.0005419894,0.0003577585,0.0006356918,0.0005810499],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003524393,"about_ca_system_score_gemma":0.0001740049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001533771,"about_ca_topic_score_gemma":0.0002631851,"domain_scores_codex":[0.9998381,0.00002168718,0.00002422147,0.00003373193,0.0000387908,0.00004348467],"domain_scores_gemma":[0.9998073,0.0000303796,0.00005875152,0.00004948856,0.00002756855,0.00002656086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009403566,0.00001505966,0.0006340321,0.00002396233,0.000002964119,0.00007463406,0.00002422325,0.00004183418,0.9970013,0.0002448188,0.00001505138,0.001828064],"study_design_scores_gemma":[0.00003023758,0.0002575103,0.003694348,0.000006744187,0.00001742672,0.001026884,0.00005306698,0.000833392,0.9920102,0.0002126255,0.001851312,0.000006264126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919717,0.0009029467,0.005720812,0.00007967325,0.0000159482,0.0000219954,0.0001767628,0.00009397639,0.001016196],"genre_scores_gemma":[0.9960067,0.0002221106,0.002347548,0.00003317206,0.000006994703,0.00002027045,0.0003043672,0.00001288833,0.001046047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008189147,"threshold_uncertainty_score":0.002739549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00804700068547337,"score_gpt":0.2131010666906388,"score_spread":0.2050540660051654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}