{"id":"W1603398350","doi":"10.1186/ar1426","title":"Different molecules at the surface of stimulated T cells induce IL-1α, tumor necrosis factor and IL-1 receptor antagonist in human monocytes","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Proinflammatory cytokine; Tumor necrosis factor alpha; Cytokine; Monocyte; Immunology; Peripheral blood mononuclear cell; Inflammation; Chemistry; Biology; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005482479,0.0006390474,0.0005945446,0.0007283238,0.0004285396,0.001064759,0.0002882055,0.0005143223,0.01217852],"category_scores_gemma":[0.0004692938,0.0003065486,0.001403366,0.0004501817,0.0002926248,0.0002696246,0.0004679008,0.0008980151,0.003467718],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003896808,"about_ca_system_score_gemma":0.000429813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005620527,"about_ca_topic_score_gemma":0.0007262664,"domain_scores_codex":[0.998989,0.0002319407,0.0001075479,0.0001395128,0.0001646369,0.0003674158],"domain_scores_gemma":[0.9997616,0.00008199927,0.00003177745,0.00003328169,0.0000424822,0.00004881215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003078277,0.0008125415,0.003491117,0.0007305872,0.00008001093,0.0006208395,0.0002909882,0.0004405208,0.9771384,0.000616572,0.001587825,0.01111224],"study_design_scores_gemma":[0.00109503,0.006765911,0.05852788,0.0002677314,0.0002228458,0.002062193,0.0008120984,0.00250796,0.9087446,0.0008811622,0.01806946,0.00004317303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9735429,0.01184935,0.004673591,0.000625016,0.0006561854,0.0002808401,0.002356185,0.0001010993,0.005914881],"genre_scores_gemma":[0.9788031,0.004187812,0.002942919,0.0006080844,0.0003715933,0.000477224,0.00424583,0.00002361102,0.008339727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01217852,"threshold_uncertainty_score":0.04074121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05223309890844941,"score_gpt":0.3462042119369137,"score_spread":0.2939711130284643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}