{"id":"W1603398350","doi":"10.1186/ar1426","title":"Different molecules at the surface of stimulated T cells induce IL-1α, tumor necrosis factor and IL-1 receptor antagonist in human monocytes","year":2004,"lang":"en","type":"article","venue":"Arthritis Research","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Arthritis Network; School of Medicine, University of California, San Diego; Menzies Institute for Medical Research; National Cancer Institute; Arthritis Society; University of North Carolina at Chapel Hill; Genentech; National Institutes of Health; Biogen; Lupus Research Institute; Pfizer; Natural Sciences and Engineering Research Council of Canada; Dutch Arthritis Association; Oesterreichische Nationalbank; Deutsche Forschungsgemeinschaft; Nuffield Foundation; Physiotherapy Foundation of Canada; Canadian Institutes of Health Research; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Lupus Research Alliance; Wellcome Trust; Newcastle University; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute; Austrian Science Fund; Arthritis Foundation","keywords":"Proinflammatory cytokine; Tumor necrosis factor alpha; Cytokine; Monocyte; Immunology; Peripheral blood mononuclear cell; Inflammation; Chemistry; Biology; Cell biology; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001124614,0.0002779028,0.0006703176,0.000345578,0.000387477,0.0001037439,0.0003691764,0.0001630347,0.0003585131],"category_scores_gemma":[0.0004253256,0.0002003448,0.0001034208,0.0007541447,0.001004934,0.0001004807,0.0005779043,0.0008659308,0.0001029451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000568613,"about_ca_system_score_gemma":0.0002553294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002650467,"about_ca_topic_score_gemma":0.001148795,"domain_scores_codex":[0.9956304,0.0005758167,0.0006695183,0.0006339948,0.001525296,0.0009650053],"domain_scores_gemma":[0.9976444,0.0007122508,0.0000997036,0.0007803316,0.0004237579,0.0003395393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003347369,0.000342611,0.05550785,0.0003873913,0.00005663978,0.0001584253,0.00287877,0.00006106166,0.9381851,0.0001164904,0.0005576254,0.0014133],"study_design_scores_gemma":[0.006511985,0.0009598936,0.0207322,0.001920301,0.000007334054,0.000419517,0.002318635,0.0002068596,0.9659419,0.0002743659,0.0004609934,0.0002459826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937174,0.002845067,0.000006066942,0.001119562,0.00006256307,0.001667261,0.0001958276,0.00003860126,0.0003476676],"genre_scores_gemma":[0.9961167,0.002412536,0.0001027127,0.00002767617,0.00004836821,0.00006986144,0.00003788032,0.00006678408,0.001117495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03477564,"threshold_uncertainty_score":0.8169824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05223309890844941,"score_gpt":0.3462042119369137,"score_spread":0.2939711130284643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}