{"id":"W1603809034","doi":"10.18632/oncotarget.3872","title":"Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion","year":2015,"lang":"en","type":"article","venue":"Oncotarget","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":141,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Protein kinase B; Viability assay; PI3K/AKT/mTOR pathway; TRPM7; Cell growth; MAPK/ERK pathway; Carvacrol; Apoptosis; MTT assay; Cell migration; Hsp27; Cell biology; Biology; Cancer research; Signal transduction; Chemistry; Cell; Heat shock protein; Hsp70; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000187447,0.0001118602,0.0001435811,0.00007352377,0.00007523851,0.00003121403,0.00003790181,0.00008745571,0.00004823272],"category_scores_gemma":[0.0001576986,0.0001071262,0.00002320283,0.0001268927,0.00004020214,0.0002795655,0.00001745289,0.00006610384,0.00001496959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004077741,"about_ca_system_score_gemma":0.00008250639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004105705,"about_ca_topic_score_gemma":0.0002444363,"domain_scores_codex":[0.9990021,0.0001036163,0.0002803576,0.0002005882,0.0002410598,0.0001722675],"domain_scores_gemma":[0.9992353,0.00004157101,0.000128604,0.0001428963,0.0001894569,0.0002621154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00365709,0.0008128929,0.3917966,0.001925825,0.000003536259,0.000007296022,0.004880728,0.00008281905,0.206499,0.00005666442,0.388881,0.001396618],"study_design_scores_gemma":[0.003652511,0.002231834,0.009609621,0.00005119725,0.00007150758,0.000008792178,0.0006677939,0.002783332,0.9579718,0.001478924,0.02112314,0.0003495822],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958919,0.0009266046,0.00008185217,0.001404482,0.0002842135,0.0003700047,0.00007008141,0.00004650067,0.0009243128],"genre_scores_gemma":[0.9987069,0.000008299557,0.0003305968,0.000483269,0.0001367391,0.00003173902,0.0001591411,0.00001400383,0.0001293568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7514728,"threshold_uncertainty_score":0.4368481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306073517067034,"score_gpt":0.2535389335885179,"score_spread":0.2404781984178476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}