{"id":"W1603809034","doi":"10.18632/oncotarget.3872","title":"Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion","year":2015,"lang":"en","type":"article","venue":"Oncotarget","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":141,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Protein kinase B; Viability assay; PI3K/AKT/mTOR pathway; TRPM7; Cell growth; MAPK/ERK pathway; Carvacrol; Apoptosis; MTT assay; Cell migration; Hsp27; Cell biology; Biology; Cancer research; Signal transduction; Chemistry; Cell; Heat shock protein; Hsp70; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007126533,0.0002414852,0.000386093,0.000262464,0.0001639813,0.0002746447,0.0001833762,0.0002239305,0.0009866557],"category_scores_gemma":[0.00008960924,0.00007762377,0.0003186943,0.0001727573,0.000172927,0.0001690583,0.0001279458,0.0005302641,0.0002897586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002562462,"about_ca_system_score_gemma":0.0003214966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008733269,"about_ca_topic_score_gemma":0.001261704,"domain_scores_codex":[0.9998785,0.00001327622,0.00001235667,0.00001226069,0.00002741015,0.00005606745],"domain_scores_gemma":[0.9999558,0.000007168097,0.00001076614,0.000004462277,0.00000839761,0.00001349089],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007094711,0.0002031545,0.0006211674,0.0001837307,0.0000194236,0.0001091352,0.00003699884,0.0001828526,0.9849061,0.0001273126,0.0005766681,0.01232399],"study_design_scores_gemma":[0.00009075244,0.002275672,0.009159055,0.00002306862,0.00006746202,0.0003178505,0.0001443345,0.002718003,0.9800439,0.00007834176,0.005070798,0.00001069181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933025,0.004010712,0.0006499631,0.000145118,0.00005469421,0.00003193831,0.0002298033,0.00009888524,0.001476294],"genre_scores_gemma":[0.9962342,0.00171904,0.000478082,0.00008560721,0.0000153823,0.00004662789,0.0003362285,0.00001041488,0.001074327],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009866557,"threshold_uncertainty_score":0.003300726,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306073517067034,"score_gpt":0.2535389335885179,"score_spread":0.2404781984178476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}