{"id":"W1604614948","doi":"10.4049/jimmunol.171.4.2035","title":"<i>Helicobacter pylori</i> Infection Interferes with Epithelial Stat6-Mediated Interleukin-4 Signal Transduction Independent of <i>cagA</i> , <i>cagE</i> , or VacA","year":2003,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Helicobacter pylori-related gastroenterology studies","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"Hospital for Sick Children","keywords":"CagA; Biology; STAT6; Signal transduction; Immune system; Helicobacter pylori; Microbiology; Tyrosine phosphorylation; Cytokine; Molecular biology; Cell biology; Interleukin 4; Immunology; Gene; Virulence; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001115089,0.0003003499,0.0001926552,0.000105594,0.00009996643,0.0002046934,0.0001589413,0.0001695948,0.001122222],"category_scores_gemma":[0.00006414534,0.0001125658,0.0002448623,0.0001103937,0.000191112,0.0001099894,0.00013622,0.0004538199,0.0003389948],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017257,"about_ca_system_score_gemma":0.0001513089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007285724,"about_ca_topic_score_gemma":0.0009077763,"domain_scores_codex":[0.9998403,0.00003536554,0.00001734922,0.00002281199,0.00003246256,0.00005165923],"domain_scores_gemma":[0.9999367,0.000009221862,0.00001717238,0.00001051083,0.00000591963,0.00002039632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001688835,0.00004318465,0.0001264764,0.000020504,0.000002570714,0.00001427519,0.000007498401,0.00002139949,0.9992094,0.0000291904,0.00002773339,0.0003287144],"study_design_scores_gemma":[0.00002583032,0.0008270658,0.009133615,0.000007074153,0.00001244083,0.0001693279,0.00003235439,0.0007692936,0.9876915,0.00001994188,0.00130805,0.00000359959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978219,0.0003791831,0.0003875644,0.00005664542,0.00001576054,0.00001188233,0.0003408881,0.00003604185,0.000950172],"genre_scores_gemma":[0.996101,0.0004300647,0.00103249,0.00005433404,0.000007748084,0.00003120314,0.0008473182,0.0000150199,0.001480774],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001122222,"threshold_uncertainty_score":0.003754258,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01323306216932941,"score_gpt":0.2389490154667872,"score_spread":0.2257159532974578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}