{"id":"W1604840148","doi":"10.1111/cmi.12165","title":"Nutrient sensing and metabolic stress pathways in innate immunity","year":2013,"lang":"en","type":"review","venue":"Cellular Microbiology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Burroughs Wellcome Fund","keywords":"Biology; Innate immune system; PI3K/AKT/mTOR pathway; AMPK; Signal transduction; Nutrient sensing; Immunity; Cell biology; Adaptation (eye); Metabolic pathway; Phosphorylation; Immunology; Immune system; Biochemistry; Neuroscience; Enzyme; Protein kinase A","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004601839,0.0009688793,0.001082065,0.001567851,0.0003076583,0.001005209,0.0008634326,0.001207296,0.003654724],"category_scores_gemma":[0.0003819049,0.000251394,0.0002953145,0.00204259,0.0006864455,0.001688304,0.0008052618,0.001821177,0.003316015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000759971,"about_ca_system_score_gemma":0.0009349065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000589832,"about_ca_topic_score_gemma":0.001076063,"domain_scores_codex":[0.999862,0.00002144676,0.00001820498,0.00002315801,0.00005774495,0.00001745381],"domain_scores_gemma":[0.9997984,0.00006472936,0.00003554651,0.000007512902,0.00005666941,0.0000372714],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005989043,0.00005058145,0.0001279107,0.007530341,0.00003810827,0.0001568283,0.00004953362,0.0003398987,0.002872526,0.005214263,0.0398781,0.943682],"study_design_scores_gemma":[0.000008108201,0.00004542491,0.0005867534,0.001673776,0.00002555612,0.0008537343,0.000046104,0.00006359464,0.0002998467,0.002973764,0.9934117,0.00001160288],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007547594,0.9983809,0.0001121939,0.0002275894,0.0002860033,0.000002521728,0.000007363265,0.000006693379,0.0009013023],"genre_scores_gemma":[0.00060762,0.9977275,0.0001616148,0.0001425914,0.0003240458,0.000004492546,0.00001877913,0.00000134096,0.001012003],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003654724,"threshold_uncertainty_score":0.01222622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03034960204397393,"score_gpt":0.2566518966257895,"score_spread":0.2263022945818155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}