{"id":"W1605572683","doi":"","title":"Altered cytokine profiles of human retinal pigment epithelium: oxidant injury and replicative senescence.","year":2013,"lang":"en","type":"article","venue":"PubMed","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Retinal pigment epithelium; Cytokine; Oxidative stress; Macular degeneration; Senescence; Stromal cell; Biology; Retinal; Interleukin 8; Andrology; Chemokine; Immunology; Cell biology; Inflammation; Endocrinology; Medicine; Cancer research; Ophthalmology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003703992,0.0002538721,0.0002001894,0.0004367208,0.0001460016,0.0003214218,0.0001112169,0.0003089221,0.0008239708],"category_scores_gemma":[0.0002581976,0.000102639,0.0002865299,0.0003057806,0.0001933529,0.0002513796,0.0002110605,0.0003131611,0.0002983743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001417918,"about_ca_system_score_gemma":0.0001330062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002988731,"about_ca_topic_score_gemma":0.0002805047,"domain_scores_codex":[0.9998112,0.00003231028,0.00002957122,0.00004422799,0.00005817981,0.00002448638],"domain_scores_gemma":[0.9997812,0.00002152619,0.00009079526,0.00002492923,0.00005755513,0.00002396227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005321326,0.00006072345,0.01188324,0.0001558015,0.00002078834,0.0003025074,0.0001844683,0.00003223574,0.9811711,0.0000249258,0.00004218144,0.005589712],"study_design_scores_gemma":[0.00002938313,0.003163188,0.3638427,0.00005763366,0.0001378255,0.0036221,0.0004058731,0.000317957,0.6236864,0.0001285393,0.004589528,0.00001897392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893656,0.008286566,0.001093077,0.00005079274,0.00002120303,0.00005747536,0.0004764529,0.00001974143,0.0006290535],"genre_scores_gemma":[0.9948495,0.002620272,0.0009662202,0.00006934538,0.00002128644,0.00005276686,0.000607317,0.000004499196,0.0008088133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008239708,"threshold_uncertainty_score":0.002756476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978055794457434,"score_gpt":0.2636650462704618,"score_spread":0.2438844883258875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}