{"id":"W1605572683","doi":"","title":"Altered cytokine profiles of human retinal pigment epithelium: oxidant injury and replicative senescence.","year":2013,"lang":"en","type":"article","venue":"PubMed","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Retinal pigment epithelium; Cytokine; Oxidative stress; Macular degeneration; Senescence; Stromal cell; Biology; Retinal; Interleukin 8; Andrology; Chemokine; Immunology; Cell biology; Inflammation; Endocrinology; Medicine; Cancer research; Ophthalmology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009295858,0.000134922,0.0002632449,0.00005914988,0.00004768585,0.00001289325,0.00005330273,0.00003525104,0.00007414204],"category_scores_gemma":[0.0000461811,0.0000960526,0.00006328651,0.00008367462,0.0001233266,0.00005797989,0.00005424499,0.00006170365,0.00001278275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004252565,"about_ca_system_score_gemma":0.00001604723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001609244,"about_ca_topic_score_gemma":8.525269e-7,"domain_scores_codex":[0.9989833,0.00003402565,0.0002585361,0.000279515,0.0001978854,0.000246696],"domain_scores_gemma":[0.9992089,0.0000188102,0.0001413582,0.000292825,0.0001068998,0.000231258],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009376809,0.001443771,0.7109106,0.0006127334,0.0004445986,0.00006000094,0.0003109076,7.463485e-8,0.09907136,0.001270704,0.002420551,0.182517],"study_design_scores_gemma":[0.0008324595,0.0003759417,0.9596118,0.00006857727,0.0001183369,0.00002374158,0.00007615718,0.000005851291,0.038303,0.000378899,0.0001215601,0.00008362341],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951977,0.0002542381,0.000007480447,0.0008780311,0.00002580603,0.001828084,0.00003646633,0.00002758946,0.001744626],"genre_scores_gemma":[0.9969068,0.000104957,0.0001987216,0.00008004168,0.00007038696,0.00188711,0.00003078526,0.00001487465,0.0007063839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2487013,"threshold_uncertainty_score":0.3916911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01978055794457434,"score_gpt":0.2636650462704618,"score_spread":0.2438844883258875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}