{"id":"W1606404504","doi":"10.1111/j.1471-4159.2006.04345.x","title":"Dopamine activates Nrf2‐regulated neuroprotective pathways in astrocytes and meningeal cells","year":2007,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Genomics, phytochemicals, and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC; Canadian Institutes of Health Research; Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Dopamine; Neuroprotection; In vivo; Oxidative stress; Monoamine neurotransmitter; Biology; Neurodegeneration; Pharmacology; Tyrosine hydroxylase; Cell biology; KEAP1; Endogeny; Chemistry; Neuroscience; Transcription factor; Serotonin; Endocrinology; Internal medicine; Biochemistry; Medicine; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001042951,0.0003124492,0.0002157082,0.0002100461,0.0001671912,0.0002336343,0.00007963784,0.0001735832,0.0008484466],"category_scores_gemma":[0.0001012368,0.0001096325,0.000250028,0.0001295347,0.0001399398,0.0001447962,0.000165399,0.0002777088,0.0002877108],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003093799,"about_ca_system_score_gemma":0.0002260465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001971728,"about_ca_topic_score_gemma":0.005368656,"domain_scores_codex":[0.9999142,0.00001401888,0.000007311771,0.00001696387,0.00002381386,0.00002374112],"domain_scores_gemma":[0.9999439,0.000005794229,0.00001140757,0.000007476041,0.00001266762,0.00001875756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001341377,0.00001434573,0.0002262942,0.00003077444,0.000005777959,0.0000913642,0.00002190793,0.00001968689,0.9985729,0.00005061746,0.00002969835,0.0008023398],"study_design_scores_gemma":[0.00004112208,0.0002178177,0.008233678,0.00000849326,0.00002160162,0.0003345803,0.0001038031,0.0004547723,0.9874127,0.0001132545,0.003052298,0.000005900606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917594,0.002102403,0.002623666,0.0001553514,0.00004167225,0.00002956262,0.0005762796,0.00003575972,0.002676097],"genre_scores_gemma":[0.9898372,0.001669326,0.003063913,0.00007641569,0.00001440981,0.00005127382,0.0006293837,0.00001240731,0.004645719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001971728,"threshold_uncertainty_score":0.003920496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007886211891907208,"score_gpt":0.2215643062217863,"score_spread":0.2136780943298791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}