{"id":"W1606803664","doi":"10.4049/jimmunol.169.1.63","title":"IL-12 Administration Leads to a Transient Depletion of T Cells, B Cells, and APCs and Concomitant Abrogation of the HLA-A2.1-Restricted CTL Response in Transgenic Mice","year":2002,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"","keywords":"Epitope; Immunodominance; Immunology; Immune system; Antigen-presenting cell; Biology; Spleen; CTL*; Genetically modified mouse; Antigen; T cell; Transgene; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002903883,0.0008693156,0.0005356118,0.0006366097,0.0002453014,0.0004673499,0.0004164866,0.0006928523,0.001685007],"category_scores_gemma":[0.0001868629,0.0003889893,0.0003451625,0.000219005,0.0005085267,0.0003258084,0.0002072358,0.002121983,0.0008322072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004436452,"about_ca_system_score_gemma":0.0002982532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005217489,"about_ca_topic_score_gemma":0.0008496082,"domain_scores_codex":[0.9995614,0.00007265536,0.00005534164,0.00008703191,0.00007777689,0.0001458862],"domain_scores_gemma":[0.9995477,0.00007173194,0.0001476871,0.00005676228,0.00002126743,0.0001550323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003125735,0.0001413173,0.0001151623,0.0000451959,0.000005358664,0.00008745051,0.00001690834,0.00006220402,0.9980261,0.0001071035,0.00005089806,0.001029698],"study_design_scores_gemma":[0.00007174411,0.0007256559,0.001450426,0.00001301194,0.00002621868,0.0003212712,0.00001642003,0.0005481258,0.9954361,0.00005063759,0.001334312,0.000005986364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912176,0.002069769,0.002906067,0.0002826561,0.000091772,0.00007003571,0.0008226903,0.0005425074,0.001996958],"genre_scores_gemma":[0.9878362,0.00137662,0.003357477,0.0001663553,0.00006899903,0.0001336523,0.001039167,0.0001091989,0.005912304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001685007,"threshold_uncertainty_score":0.005636871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01616148296063728,"score_gpt":0.2420618674585235,"score_spread":0.2259003844978862,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}