{"id":"W1608269846","doi":"10.1002/cncr.29082","title":"Intermediate clinical endpoints: A bridge between progression‐free survival and overall survival in ovarian cancer trials","year":2014,"lang":"en","type":"review","venue":"Cancer","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Clinical endpoint; Ovarian cancer; Oncology; Clinical trial; Internal medicine; Progression-free survival; Cancer; Disease; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.004275648,0.000924614,0.008705636,0.0003150605,0.00006658123,0.0000909178,0.0004071546,0.0008557844,0.0008372554],"category_scores_gemma":[0.001263743,0.0006365485,0.001150753,0.0003324646,0.0002526239,0.00009773962,0.0003519933,0.001146207,0.00003719546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009362897,"about_ca_system_score_gemma":0.001946865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009614817,"about_ca_topic_score_gemma":0.0009801028,"domain_scores_codex":[0.9925764,0.001699354,0.002907826,0.001417952,0.0006491061,0.0007493363],"domain_scores_gemma":[0.9943478,0.002444225,0.001351263,0.001109338,0.0001242744,0.0006230839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001755409,0.0002273433,0.04898179,0.008343586,0.001624868,0.0001311772,0.00004411941,9.372871e-8,7.182224e-8,0.0001389251,0.006157964,0.9341745],"study_design_scores_gemma":[0.008272223,0.0003309149,0.07898993,0.04604124,0.004793284,0.000008863559,0.000003934922,0.000001627747,0.000001280223,0.0000822843,0.8609168,0.0005575972],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004150034,0.9885871,0.00001757621,0.001297852,0.004193667,0.003180651,0.001494984,0.00005921032,0.0007539091],"genre_scores_gemma":[0.0007484502,0.9882506,0.00009915989,0.0002506562,0.007169159,0.002566593,0.0003205975,0.0001697568,0.0004250898],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9336169,"threshold_uncertainty_score":0.9996086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2417919952149547,"score_gpt":0.5021888484501298,"score_spread":0.260396853235175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}