{"id":"W1608345078","doi":"10.1038/ng574","title":"Imprinted X inactivation maintained by a mouse Polycomb group gene","year":2001,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":338,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Calgary","funders":"","keywords":"Biology; X-inactivation; Embryonic stem cell; Dosage compensation; XIST; Genomic imprinting; Genetics; Transgene; Embryo; Gene; Molecular biology; Gene silencing; X chromosome; Chromosome; Cell biology; Embryogenesis; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002503154,0.000493753,0.0003106132,0.0007671973,0.0003718914,0.0005887059,0.0009006697,0.0005289284,0.002495568],"category_scores_gemma":[0.0002735356,0.0004791786,0.0003250337,0.0003785049,0.0007650684,0.0003697119,0.0005957536,0.0008511883,0.0008041453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004537864,"about_ca_system_score_gemma":0.000223731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007408059,"about_ca_topic_score_gemma":0.001421573,"domain_scores_codex":[0.9996363,0.00003784758,0.00002543352,0.00009385689,0.0001158541,0.00009077917],"domain_scores_gemma":[0.9995053,0.0000757029,0.0001629219,0.0001116778,0.00002696838,0.00011749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001744457,0.00001559705,0.0002871135,0.00001513966,0.000007891259,0.0001879653,0.00002003287,0.00003721509,0.9976502,0.0007359967,0.00004073433,0.0008277228],"study_design_scores_gemma":[0.00005516409,0.0001546779,0.007105238,0.000005398856,0.00003761513,0.0007808912,0.00003109082,0.0003809998,0.9891874,0.000249068,0.002006389,0.00000600324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893658,0.001393181,0.004069044,0.0001678115,0.00008455644,0.00002308985,0.000297044,0.0002851239,0.004314307],"genre_scores_gemma":[0.9902183,0.0003915067,0.001224006,0.00004339661,0.00002285071,0.00002230422,0.0003068818,0.00008003613,0.007690616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002495568,"threshold_uncertainty_score":0.008348465,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004697688994039703,"score_gpt":0.2464759777629352,"score_spread":0.2417782887688955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}