{"id":"W1608345078","doi":"10.1038/ng574","title":"Imprinted X inactivation maintained by a mouse Polycomb group gene","year":2001,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":338,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute; University of Calgary","funders":"","keywords":"Biology; X-inactivation; Embryonic stem cell; Dosage compensation; XIST; Genomic imprinting; Genetics; Transgene; Embryo; Gene; Molecular biology; Gene silencing; X chromosome; Chromosome; Cell biology; Embryogenesis; DNA methylation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001735328,0.0002198463,0.0001411431,0.00006656022,0.00009675376,0.00003851039,0.0002259649,0.0006266431,0.00002601631],"category_scores_gemma":[0.00009096823,0.000223993,0.00008594813,0.0001903285,0.00004485233,0.000003675748,0.0001080997,0.00028917,0.00000934162],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003950646,"about_ca_system_score_gemma":0.00003688873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000180912,"about_ca_topic_score_gemma":0.00002855185,"domain_scores_codex":[0.9987175,0.0000633375,0.0002467347,0.000432867,0.0002205375,0.0003189802],"domain_scores_gemma":[0.9991323,0.00001147279,0.0001142892,0.0004724836,0.0001469243,0.0001225783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008840685,0.00008532132,0.005453947,0.000004828494,0.00003645639,0.000002181391,0.00001834605,0.00005976607,0.9886481,0.00004382842,0.001076686,0.004482138],"study_design_scores_gemma":[0.0006042943,0.0002817689,0.00450939,0.000003090271,0.00001668108,0.000006735118,0.00002713254,0.0002636215,0.900601,0.0002479737,0.09317952,0.0002588208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9719092,0.006503669,0.02021669,0.0002006339,0.000241904,0.0002359494,0.00003492978,0.00002877407,0.0006282391],"genre_scores_gemma":[0.99085,0.002614342,0.003685189,0.0004718582,0.0003890671,0.00001738985,0.0009154962,0.00004952744,0.001007122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09210283,"threshold_uncertainty_score":0.9134169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004697688994039703,"score_gpt":0.2464759777629352,"score_spread":0.2417782887688955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}