{"id":"W1609911096","doi":"10.1016/j.jcf.2015.03.004","title":"Tiotropium Respimat® in cystic fibrosis: Phase 3 and Pooled phase 2/3 randomized trials","year":2015,"lang":"eo","type":"article","venue":"Journal of Cystic Fibrosis","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; University of Toronto","funders":"","keywords":"Medicine; Placebo; Cystic fibrosis; Internal medicine; Adverse effect; Clinical trial; Lung function; Spirometry; Randomized controlled trial; Phases of clinical research; Clinical endpoint; Lung; Asthma; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007097383,0.002770591,0.007039029,0.0008559366,0.0006714707,0.002034282,0.001107378,0.002267061,0.005797102],"category_scores_gemma":[0.006364023,0.0009320342,0.0121934,0.0009371588,0.001118966,0.001649605,0.0008717419,0.003451794,0.0006950562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001523482,"about_ca_system_score_gemma":0.002014022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001765456,"about_ca_topic_score_gemma":0.005062476,"domain_scores_codex":[0.9970209,0.001787071,0.0003411722,0.0003326773,0.0002352067,0.0002828862],"domain_scores_gemma":[0.9971251,0.001235017,0.0008698675,0.0002353511,0.0002150161,0.0003196355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9088949,0.001157388,0.00083376,0.01144824,0.03961078,0.00006536031,0.0000763392,0.0005813462,0.002349032,0.000201512,0.002357221,0.03242411],"study_design_scores_gemma":[0.9525926,0.01715303,0.002097944,0.0006070617,0.02527142,0.00004803063,0.00003597311,0.0001807439,0.0002971605,0.000284436,0.001400986,0.00003064307],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5793443,0.3708684,0.007161688,0.005019782,0.004023773,0.0188251,0.007460007,0.0006215785,0.006675331],"genre_scores_gemma":[0.8868887,0.07986663,0.0064852,0.004988168,0.001693391,0.01301673,0.00324248,0.0001274487,0.003691317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007097383,"threshold_uncertainty_score":0.03753495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05670319416127625,"score_gpt":0.4015925632444183,"score_spread":0.3448893690831421,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}