{"id":"W1610547722","doi":"","title":"Relationship of intracellular glutathione concentrations with the cytotoxicity of cisplatin, acetaminophen and arsenic in tumor cell lines","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Cisplatin; Cytotoxicity; Clonogenic assay; Glutathione; Cytotoxic T cell; Cell culture; Acetaminophen; Chemistry; Pharmacology; Intracellular; A549 cell; Toxicology; Cell; Biochemistry; In vitro; Biology; Chemotherapy; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001890843,0.0003089863,0.0003253787,0.0007669755,0.000171637,0.0003044995,0.000176659,0.0002979283,0.001933114],"category_scores_gemma":[0.0003363275,0.0001722208,0.0002185044,0.001018443,0.0001518825,0.0002190553,0.0001696377,0.000665427,0.0007867237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002839873,"about_ca_system_score_gemma":0.0001844374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001584723,"about_ca_topic_score_gemma":0.001745128,"domain_scores_codex":[0.9997829,0.00004515563,0.00003445174,0.00003426937,0.00007153231,0.00003174451],"domain_scores_gemma":[0.9996455,0.0001032525,0.00006375802,0.00003789951,0.0001041493,0.00004551108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001110675,0.0002247974,0.02061394,0.000121402,0.0001095076,0.0003243838,0.0001655735,0.0004383049,0.9648854,0.0001519372,0.001128691,0.01072543],"study_design_scores_gemma":[0.00002831511,0.001942847,0.1599151,0.00001489401,0.0001381145,0.00134092,0.0002474633,0.001794804,0.828553,0.0001242405,0.005877191,0.00002316513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827989,0.008248948,0.002506375,0.0002153006,0.00006447614,0.00005788076,0.002348294,0.0001824916,0.003577295],"genre_scores_gemma":[0.9873213,0.002798693,0.001976784,0.00006564237,0.0000225269,0.00009249813,0.003988297,0.00001864002,0.003715776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001933114,"threshold_uncertainty_score":0.006466985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145041461949805,"score_gpt":0.3148066879028444,"score_spread":0.2833562732833464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}