{"id":"W1610547722","doi":"","title":"Relationship of intracellular glutathione concentrations with the cytotoxicity of cisplatin, acetaminophen and arsenic in tumor cell lines","year":2005,"lang":"en","type":"article","venue":"Cancer Research","topic":"Glutathione Transferases and Polymorphisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Cisplatin; Cytotoxicity; Clonogenic assay; Glutathione; Cytotoxic T cell; Cell culture; Acetaminophen; Chemistry; Pharmacology; Intracellular; A549 cell; Toxicology; Cell; Biochemistry; In vitro; Biology; Chemotherapy; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003816966,0.00007306248,0.0001103351,0.00004912856,0.00007320847,0.00000806458,0.0001160168,0.00005523596,0.00002539086],"category_scores_gemma":[0.00003733005,0.00005181445,0.00002472501,0.0002014821,0.0003294984,0.000005859367,0.00003160664,0.0001919146,0.000001023732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001405263,"about_ca_system_score_gemma":0.000180199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000147956,"about_ca_topic_score_gemma":0.0007460377,"domain_scores_codex":[0.999158,0.00012798,0.0001828964,0.0001664751,0.000183222,0.0001814648],"domain_scores_gemma":[0.9994849,0.00009018469,0.0000463497,0.0001937953,0.0001402333,0.000044519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001684976,0.00005882714,0.01777614,0.00004526645,0.00001014773,0.000001713799,0.0004147379,0.0009609045,0.9798142,0.0003993782,0.0001056552,0.0002445403],"study_design_scores_gemma":[0.0007723128,0.0002388448,0.02871799,0.00003176411,0.00001144517,0.000005042296,0.0002732497,0.0002181879,0.9690582,0.00003610384,0.0005626308,0.00007428561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942861,0.004058436,0.0002441093,0.000953187,0.000009012485,0.0002751421,0.0000363382,0.000001799406,0.0001358637],"genre_scores_gemma":[0.9990251,0.0003682479,0.0002226528,0.00003317561,0.00006434048,0.00004317365,0.00001391665,0.000009805507,0.0002195671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01094186,"threshold_uncertainty_score":0.2112932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03145041461949805,"score_gpt":0.3148066879028444,"score_spread":0.2833562732833464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}