{"id":"W1613199604","doi":"10.1002/ijc.28473","title":"S100A7 overexpression is a predictive marker for high risk of malignant transformation in oral dysplasia","year":2013,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Oral Health Pathology and Treatment","field":"Dentistry","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Toronto; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Cancer; Dysplasia; Internal medicine; Oncology; Biomarker; Biopsy; Hazard ratio; Proportional hazards model; Surrogate endpoint; Pathology; Biology; Confidence interval","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003865788,0.0002285917,0.0002543649,0.001049257,0.0002183792,0.0003903247,0.0001244294,0.0002580652,0.0007011009],"category_scores_gemma":[0.0009859059,0.0001787044,0.0002052158,0.0005267537,0.0002447274,0.000168269,0.0002842311,0.0002165709,0.0001826743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001534452,"about_ca_system_score_gemma":0.0001592298,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000943595,"about_ca_topic_score_gemma":0.00123724,"domain_scores_codex":[0.9998635,0.00003948195,0.00001777361,0.00002148448,0.00003352401,0.00002430127],"domain_scores_gemma":[0.9995226,0.0001413436,0.0001626618,0.0000282341,0.00007934822,0.00006592046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002518618,0.0000141527,0.9921949,0.00001380209,0.00001883637,0.0001460112,0.00002450623,0.0000657854,0.003853338,0.000009694041,0.00002679252,0.0033803],"study_design_scores_gemma":[0.000004484931,0.00013708,0.9963413,0.000006412364,0.00004254385,0.001109312,0.00009418964,0.0005574058,0.001491985,0.0000377523,0.0001745531,0.000002868776],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991602,0.0004749469,0.000137794,0.000009444977,0.000002063566,0.000003655692,0.00002452515,0.000004233125,0.0001831504],"genre_scores_gemma":[0.9996454,0.0001296094,0.0001103755,0.000003035757,0.000002732379,0.000002142598,0.00004507959,7.375048e-7,0.00006088632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001049257,"threshold_uncertainty_score":0.002345383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139488232643722,"score_gpt":0.342462900523328,"score_spread":0.3285140772589558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}