{"id":"W1613232352","doi":"10.1016/j.mce.2015.09.008","title":"Inhibition of c-Src/p38 MAPK pathway ameliorates renal tubular epithelial cells apoptosis in db/db mice","year":2015,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; London Health Sciences Centre; Lawson Health Research Institute","funders":"Hebei Provincial Health and Family Planning Commission; National Natural Science Foundation of China","keywords":"Apoptosis; p38 mitogen-activated protein kinases; MAPK/ERK pathway; Kidney; Endocrinology; Internal medicine; Proto-oncogene tyrosine-protein kinase Src; TUNEL assay; Creatinine; Biology; Chemistry; Cancer research; Phosphorylation; Cell biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006144119,0.001547858,0.001416478,0.001617628,0.0007766126,0.0007933178,0.001103091,0.00115809,0.004379161],"category_scores_gemma":[0.0002411364,0.0008135747,0.001377324,0.0006710335,0.001001685,0.0008710656,0.0005013639,0.003998419,0.001024039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006002451,"about_ca_system_score_gemma":0.0009758375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002458192,"about_ca_topic_score_gemma":0.002986156,"domain_scores_codex":[0.9990621,0.0001067969,0.0001320376,0.0001980678,0.000169374,0.0003315948],"domain_scores_gemma":[0.9993141,0.00002616425,0.0001813675,0.00005909738,0.00006032881,0.0003590296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005866086,0.001020188,0.0006374232,0.0002176361,0.00008967436,0.0003232585,0.00005873388,0.0001715628,0.987738,0.0005045326,0.0004489426,0.002923963],"study_design_scores_gemma":[0.0008918818,0.002878675,0.01036722,0.00004226585,0.0004348793,0.001402356,0.0003698854,0.00253573,0.9735338,0.0004676189,0.007022242,0.00005342736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9876814,0.002749855,0.004221614,0.0009399781,0.0004072765,0.00007743377,0.00130457,0.0006212527,0.001996685],"genre_scores_gemma":[0.9827588,0.003009652,0.002746871,0.0004283178,0.0001647359,0.0002163518,0.001290605,0.0001802375,0.0092044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004379161,"threshold_uncertainty_score":0.01464975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134298483885692,"score_gpt":0.2271920372265823,"score_spread":0.2158490523877254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}