{"id":"W1616649922","doi":"10.1038/35037747","title":"From bench to clinic with apoptosis-based therapeutic agents","year":2000,"lang":"en","type":"review","venue":"Nature","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":692,"is_retracted":false,"has_abstract":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Pace; Disease; Apoptosis; Medicine; Bench to bedside; Bioinformatics; Biology; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001388562,0.00209828,0.002136667,0.002227133,0.000704911,0.001914688,0.002189336,0.003012964,0.005938648],"category_scores_gemma":[0.0009244874,0.000486433,0.000700318,0.001788923,0.001652164,0.003389506,0.001046376,0.005455851,0.005692599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001241914,"about_ca_system_score_gemma":0.0007641307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006980557,"about_ca_topic_score_gemma":0.002417096,"domain_scores_codex":[0.9996265,0.00006303662,0.0000365482,0.00007053912,0.0001660662,0.00003724467],"domain_scores_gemma":[0.9995822,0.0002262205,0.00003488986,0.00002258417,0.00008794854,0.00004610783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001879171,0.0002232031,0.0001309403,0.004683196,0.00006248967,0.0005571458,0.00007552213,0.0006717241,0.005826275,0.01053413,0.08691754,0.8901299],"study_design_scores_gemma":[0.00006546462,0.0001584834,0.000221771,0.0008177355,0.00005754358,0.001724123,0.00003858094,0.0001877738,0.001562206,0.004110652,0.9910359,0.00001974393],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002272695,0.9883795,0.002201634,0.001450269,0.001708393,0.00002658219,0.00002291508,0.00006450334,0.005918973],"genre_scores_gemma":[0.002044443,0.9840372,0.002634389,0.002725834,0.00148242,0.00007036513,0.00006714171,0.000016825,0.006921416],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005938648,"threshold_uncertainty_score":0.01986676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02108382055601177,"score_gpt":0.3320067156063153,"score_spread":0.3109228950503036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}