{"id":"W1620095942","doi":"10.1016/j.chemphyslip.2015.09.002","title":"A calorimetric and spectroscopic comparison of the effects of cholesterol and its immediate biosynthetic precursors 7-dehydrocholesterol and desmosterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes","year":2015,"lang":"en","type":"article","venue":"Chemistry and Physics of Lipids","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Dipalmitoylphosphatidylcholine; Thermotropic crystal; Desmosterol; Bilayer; Membrane; Differential scanning calorimetry; Phase (matter); Crystallography; Cooperativity; Phospholipid; Analytical Chemistry (journal); Cholesterol; Chromatography; Thermodynamics; Organic chemistry; Sterol; Biochemistry; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007638754,0.0001824346,0.000315803,0.00001277209,0.00004207433,0.00001090946,0.0001064323,0.0001184987,0.000001236441],"category_scores_gemma":[0.00009934435,0.0001168013,0.00002823914,0.000128919,0.0003222848,0.00001152153,0.0001120542,0.0000959996,2.426721e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002831467,"about_ca_system_score_gemma":0.00002436751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007831199,"about_ca_topic_score_gemma":6.188519e-7,"domain_scores_codex":[0.9992266,0.00004351012,0.0002555629,0.0002341534,0.0001316279,0.0001085057],"domain_scores_gemma":[0.9992686,0.00006764193,0.00026074,0.0002315503,0.00009895205,0.00007253249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006259578,0.0001629521,0.05711527,0.0006714953,0.00003535578,8.666289e-8,0.000459388,9.324276e-7,0.9398147,0.000006896383,0.000002803063,0.001667543],"study_design_scores_gemma":[0.001719173,0.0003973013,0.02584968,0.0001204529,0.0002246105,0.000005787248,0.00007461409,0.00002558415,0.9714628,0.00001590562,0.000007031041,0.00009701657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998194,0.001331521,0.000008280339,0.00003117121,0.00006510154,0.0003216366,0.00003366369,0.000002411025,0.00001223381],"genre_scores_gemma":[0.9994836,0.0003491257,0.00001431307,0.00001679755,0.00008250251,0.000007745648,0.00001466413,0.00001497924,0.00001624995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03164816,"threshold_uncertainty_score":0.4763017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224878095551489,"score_gpt":0.2634664675947325,"score_spread":0.2512176866392176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}