{"id":"W1620095942","doi":"10.1016/j.chemphyslip.2015.09.002","title":"A calorimetric and spectroscopic comparison of the effects of cholesterol and its immediate biosynthetic precursors 7-dehydrocholesterol and desmosterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes","year":2015,"lang":"en","type":"article","venue":"Chemistry and Physics of Lipids","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Dipalmitoylphosphatidylcholine; Thermotropic crystal; Desmosterol; Bilayer; Membrane; Differential scanning calorimetry; Phase (matter); Crystallography; Cooperativity; Phospholipid; Analytical Chemistry (journal); Cholesterol; Chromatography; Thermodynamics; Organic chemistry; Sterol; Biochemistry; Phosphatidylcholine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001661056,0.0001635299,0.0001372147,0.0001698478,0.0002342593,0.0001717329,0.0002125973,0.0002279433,0.00141944],"category_scores_gemma":[0.0004173534,0.0001454863,0.000158729,0.0001896295,0.0003415816,0.0001669472,0.0001437873,0.0003924273,0.0001482245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002584072,"about_ca_system_score_gemma":0.000214054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001239532,"about_ca_topic_score_gemma":0.00124472,"domain_scores_codex":[0.9999075,0.00001941961,0.00000502224,0.00001210161,0.00003638071,0.00001960809],"domain_scores_gemma":[0.9997254,0.0001064483,0.00003514711,0.00002571972,0.00006603105,0.00004120639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000214938,0.00002140344,0.0001808013,0.00001375976,0.000004159012,0.00001469483,0.00002024285,0.00006168481,0.9987772,0.00007275077,0.00002186565,0.000596496],"study_design_scores_gemma":[0.00000855542,0.00008696487,0.004160961,0.000001421015,0.000006932323,0.00005467399,0.00001944741,0.0006379285,0.994758,0.00002639926,0.000234461,0.000004265605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971753,0.0004788974,0.0007863162,0.0000647799,0.0000133441,0.00001165396,0.0001873641,0.00001878428,0.001263495],"genre_scores_gemma":[0.9980786,0.0002673728,0.0005700609,0.00003595527,0.000006948701,0.00001196041,0.0002581018,0.000008334156,0.0007626745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00141944,"threshold_uncertainty_score":0.004748464,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224878095551489,"score_gpt":0.2634664675947325,"score_spread":0.2512176866392176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}