{"id":"W1621615533","doi":"","title":"HER-2/neu is a tumor rejection target in tolerized HER-2/neu transgenic mice.","year":2000,"lang":"en","type":"article","venue":"PubMed","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":216,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"HER2/neu; Transgene; Immune system; Genetically modified mouse; Biology; Immunology; Oncogene; Vaccination; Cancer research; Immune tolerance; Cancer; Breast cancer; Cell cycle; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005289954,0.0003188897,0.0004913573,0.0002321887,0.0001934763,0.00003391306,0.0003358316,0.0003104868,0.006184877],"category_scores_gemma":[0.00004358257,0.0003044684,0.0002425064,0.0004220507,0.0001805479,0.0002296212,0.00002016844,0.0004916326,0.000762392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001037801,"about_ca_system_score_gemma":0.00006680366,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004215859,"about_ca_topic_score_gemma":0.000047752,"domain_scores_codex":[0.9974466,0.000547134,0.0005652989,0.0004810619,0.00005802982,0.0009018814],"domain_scores_gemma":[0.9992864,0.0001249451,0.0001017599,0.0004205905,0.00003229394,0.00003408134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01509698,0.001146702,0.00227985,0.00006161337,0.0006467863,0.00003270166,0.003973272,0.00001841604,0.5613507,0.00004803107,0.007691917,0.407653],"study_design_scores_gemma":[0.007207928,0.0002059234,0.1738408,0.00003623909,0.00004465907,0.0002050994,0.0002371671,0.000004289989,0.2849988,0.0001885392,0.5324309,0.0005996131],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981454,0.0111808,0.00002200662,0.0008888518,0.001013219,0.001037255,0.00003462386,0.0001642993,0.004204962],"genre_scores_gemma":[0.9616266,0.0007440249,0.00003796681,0.001422032,0.00005891881,0.001161946,0.00004801053,0.00004823058,0.03485227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.524739,"threshold_uncertainty_score":0.9999408,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01154389851965504,"score_gpt":0.2081733303930755,"score_spread":0.1966294318734204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}